Trifluoroacetic Acid

Trifluoroacetic Acid

SCHEMBL1628375

O=C(O)C(F)(F)F.O=CO

nearest known ligand 0.36

Full drug profile on Sugi Atlas →

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
THRB P10828 1/20 0.35
TSHR P16473 2/20 0.33
TP53 P04637 1/20 0.33
CA2 P00918 1/20 0.33
CES1 P23141 1/20 0.32
ACLY P53396 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Trifluoroacetic Acid SCHEMBL11039617 0.97 ALDH1A1 (0.35) ALDH1A1L3MBTL1THRBTSHRTP53
Trifluoroacetic Acid SCHEMBL30699576 0.97 ALDH1A1 (0.35) ALDH1A1L3MBTL1THRBTSHRTP53
Trifluoroacetic Acid SCHEMBL27753577 0.97 ALDH1A1 (0.35) ALDH1A1L3MBTL1THRBTSHRTP53
Trifluoroacetic Acid SCHEMBL5583768 0.94 ALDH1A1 (0.33) ALDH1A1L3MBTL1THRBTSHRTP53
Trifluoroacetic Acid SCHEMBL30657022 0.84
Trifluoroacetic Acid SCHEMBL4598430 0.84
Trifluoroacetic Acid SCHEMBL7814389 0.84 ALDH1A1 (0.44) ALDH1A1L3MBTL1THRBTSHRTP53
Trifluoroacetic Acid SCHEMBL2484766 0.84 ALDH1A1 (0.44) ALDH1A1L3MBTL1THRBTSHRTP53
Trifluoroacetic Acid SCHEMBL474 0.84
Trifluoroacetic Acid SCHEMBL31127616 0.83 ALDH1A1 (0.35) ALDH1A1L3MBTL1THRBTSHRTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 61 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4161931-B1 NOVEL IMIDAZOPYRAZINE DERIVATIVES HOFFMANN LA ROCHE (CH) 2026-02-18 EP claimed
CN-111944104-B Porous double-template molecularly imprinted polymer microsphere for detecting dengue NS1 protein and application thereof 华南师范大学 2022-06-21 CN claimed
CN-111944104-A Porous double-template molecularly imprinted polymer microsphere for detecting dengue NS1 protein and application thereof 华南师范大学 2020-11-17 CN claimed
EP-0570849-B1 Process for the cleavage of cephalosporin prodrug esters to 7-amino-3-methoxymethylceph-3-em-4-carboxylic acid HOECHST AG (DE) 1998-03-25 EP claimed
US-5410042-A Process for the cleavage of cephalosporin prodrug esters to 7-amino-3-methoxymethylceph-3-em-4-carboxylic acid HOECHST AKTIENGESELLSCHAFT (DE) 1995-04-25 US claimed
EP-4161931-B1 NOVEL IMIDAZOPYRAZINE DERIVATIVES HOFFMANN LA ROCHE (CH) 2026-02-18 EP disclosed
US-20240218011-A1 GLUCOCORTICOID RECEPTOR AGONISTS AND CONJUGATES THEREOF FIREFLY BIO, INC. 2024-07-04 US disclosed
US-20240067640-A1 PHENYL MALEIMIDE LINKER AGENTS FIREFLY BIO, INC. 2024-02-29 US disclosed
WO-2024020164-A2 GLUCOCORTICOID RECEPTOR AGONISTS AND CONJUGATES THEREOF FIREFLY BIO, INC. (US) 2024-01-25 WO disclosed
WO-2024012519-A1 PAN-KRAS INHIBITOR 北京华森英诺生物科技有限公司 2024-01-18 WO disclosed
CN-117024423-A Synthetic method of 3, 4-dihydro-isocoumarin-beta-carboline hybrid and analogue thereof 伊犁师范大学 2023-11-10 CN disclosed
WO-2023173121-A1 PHENYL MALEIMIDE LINKER AGENTS FIREFLY BIO, INC. (US) 2023-09-14 WO disclosed
CN-101657437-A Novel method for preparing levocetirizine and intermediate thereof KRKA TORVARNA ZDRAVIL D D NOVO 2010-02-24 CN disclosed
US-20090170790-A1 KETOLIDE DERIVATIVES AS ANTIBACTERIAL AGENTS RANBAXY LABORATORIES LIMITED (IN) 2009-07-02 US disclosed
EP-1807439-A2 KETOLIDE DERIVATIVES AS ANTIBACTERIAL AGENTS Ranbaxy Laboratories Limited (IN) 2007-07-18 EP disclosed
WO-2006046112-A2 KETOLIDE DERIVATIVES AS ANTIBACTERIAL AGENTS RANBAXY LABORATORIES LIMITED (IN) 2006-05-04 WO disclosed
WO-2004112714-A2 CHEMICAL COMPOUNDS SMITHKLINE BEECHAM CORPORATION (US) 2004-12-29 WO disclosed
CN-1214039-A Carbamoyloxy derivatives of mutiline and their use as antibacterials SMITHKLINE BEECHAM PLC (GB) 1999-04-14 CN disclosed
US-5410042-A Process for the cleavage of cephalosporin prodrug esters to 7-amino-3-methoxymethylceph-3-em-4-carboxylic acid HOECHST AKTIENGESELLSCHAFT (DE) 1995-04-25 US disclosed
US-4165316-A Process for preparing sulfinyl chlorides from penicillin sulfoxides ELI LILLY AND COMPANY (US) 1979-08-21 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240218011-A1 GLUCOCORTICOID RECEPTOR AGONISTS AND CONJUGATES THEREOF NR3C1, NR3C2, MC2R ALDH1A1 3778/4885L3MBTL1 4185/4885THRB 195/4885
US-20090170790-A1 KETOLIDE DERIVATIVES AS ANTIBACTERIAL AGENTS MGAM, HEXA, MGAM2 ALDH1A1 2673/4885L3MBTL1 2923/4885THRB 2174/4885
US-20240067640-A1 PHENYL MALEIMIDE LINKER AGENTS TPX2, H1-4, MAPT ALDH1A1 4502/4885L3MBTL1 816/4885THRB 251/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.