SCHEMBL16284292

SCHEMBL16284292

COCN1C(=O)N(C)C2C1N(CCO)C(=O)N2CCO

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.44
GAA P10253 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.38
TSHR P16473 1/20 0.36
ADRA2C P18825 1/20 0.34
MAPK1 P28482 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15429213 0.97 TP53 (0.47) TP53GAAL3MBTL1TSHRADRA2C
SCHEMBL6124091 0.93 L3MBTL1 (0.42) TP53GAAL3MBTL1ADRA2C
SCHEMBL9999899 0.93 L3MBTL1 (0.42) TP53GAAL3MBTL1ADRA2C
SCHEMBL12316951 0.89 GAA (0.48) TP53GAAL3MBTL1TSHRADRA2C
SCHEMBL12368490 0.87 L3MBTL1 (0.55) TP53GAAL3MBTL1
SCHEMBL15033912 0.87 L3MBTL1 (0.55) TP53GAAL3MBTL1
SCHEMBL17807665 0.87 L3MBTL1 (0.55) TP53GAAL3MBTL1
SCHEMBL15434301 0.86 GAA (0.52) TP53GAAL3MBTL1TSHRADRA2C
SCHEMBL9973242 0.84 ADRA2C (0.50) TP53GAAL3MBTL1TSHRADRA2C
SCHEMBL15085745 0.84 ADRA2C (0.50) TP53GAAL3MBTL1TSHRADRA2C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9862805-B2 Engineered cross-linked thermoplastic particles for interlaminar toughening CYTEC TECHNOLOGY CORP. (US) 2018-01-09 US disclosed
US-20140364568-A1 ENGINEERED CROSS-LINKED THERMOPLASTIC PARTICLES FOR INTERLAMINAR TOUGHENING CYTEC TECHNOLOGY CORP. (US) 2014-12-11 US disclosed