Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TRIM58 | Q8NG06 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | SRC | P12931 | 1/20 | 0.39 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4407012 | 0.72 | ALDH1A1 (0.48) | TDP1KDM4EALDH1A1L3MBTL1HPGD | |
| SCHEMBL17612628 | 0.72 | KDM4E (0.44) | TDP1KDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL16285514 | 0.71 | PLK1 (0.42) | TDP1KDM4EALDH1A1GAAL3MBTL1 | |
| SCHEMBL5336795 | 0.69 | KDM4E (0.52) | TDP1KDM4EALDH1A1GAAGLA | |
| SCHEMBL5408033 | 0.68 | KDM4E (0.51) | KDM4ETDO2LMNAHTTMEN1 | |
| SCHEMBL29007295 | 0.68 | ADORA3 (0.59) | TDP1KDM4EALDH1A1GAAGLA | |
| SCHEMBL2189712 | 0.67 | ALDH1A1 (0.56) | KDM4EALDH1A1GAAGLAL3MBTL1 | |
| SCHEMBL12172515 | 0.66 | MKNK2 (0.50) | TDP1KDM4EALDH1A1GAAGLA | |
| SCHEMBL15301870 | 0.64 | TDO2 (0.39) | TDP1KDM4EALDH1A1GAAGLA | |
| SCHEMBL7242492 | 0.64 | TDP1 (0.55) | TDP1KDM4EALDH1A1GAAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140361285-A1 | MONOAMINE COMPOUND, CHARGE-TRANSPORTING MATERIAL, AND ORGANIC ELECTROLUMINESCENT DEVICE | MITSUBISHI CHEMICAL CORPORATION (JP) | 2014-12-11 | — | — | US | disclosed |