Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.36 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.35 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.35 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.35 |
| ▸ | CCKBR | P32239 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | HTR2B | P41595 | 1/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10345602 | 0.81 | NR1H3 (0.35) | ALDH1A1KDM4EHPGDMAPTLMNA | |
| SCHEMBL16286120 | 0.78 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDTTRCES1 | |
| SCHEMBL3368766 | 0.69 | MEN1 (0.35) | ALDH1A1KDM4EHPGDCES1MAPT | |
| SCHEMBL13391522 | 0.67 | KDM4E (0.57) | ALDH1A1KDM4EHPGDTTRCES1 | |
| Iodide SCHEMBL29133261 | 0.67 | GAA (0.39) | ALDH1A1KDM4EHPGDMAPTLMNA | |
| SCHEMBL17275723 | 0.66 | ALDH1A1 (0.50) | ALDH1A1KDM4EHPGDTTRCES1 | |
| SCHEMBL15216876 | 0.66 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDTTRCES1 | |
| SCHEMBL15216880 | 0.66 | IDO1 (0.39) | ALDH1A1HPGDMAPTKMT2AMEN1 | |
| SCHEMBL15216879 | 0.66 | ACHE (0.43) | ALDH1A1KDM4EMAPTLMNAHTT | |
| SCHEMBL15216881 | 0.66 | ALDH1A1 (0.42) | ALDH1A1KDM4EHPGDMAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140364430-A1 | METHODS FOR TREATING SCHIZOPHRENIA | AFRAXIS HOLDINGS INC (US) | 2014-12-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140364430-A1 | METHODS FOR TREATING SCHIZOPHRENIA | GRIN2A, GRIN2C, GRIN3A | ALDH1A1 2796/4885KDM4E 3382/4885HPGD 2207/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.