Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H3 | Q13133 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | SNCA | P37840 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | GPR3 | P46089 | 1/20 | 0.31 |
| ▸ | IDO1 | P14902 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16285651 | 0.81 | ALDH1A1 (0.40) | NR1H3ALDH1A1GAALMNAPAX8 | |
| Iodide SCHEMBL29133261 | 0.67 | GAA (0.39) | ALDH1A1GAALMNAPAX8MCL1 | |
| SCHEMBL8911633 | 0.66 | LMNA (0.41) | NR1H3ALDH1A1GAALMNAPAX8 | |
| SCHEMBL10345638 | 0.66 | ALDH1A1 (0.39) | ALDH1A1L3MBTL1KDM4EHPGDHSD17B10 | |
| SCHEMBL10346066 | 0.66 | IDO1 (0.31) | ALDH1A1GAALMNAKDM4EMAPT | |
| SCHEMBL10346127 | 0.66 | ADRA2A (0.33) | NR1H3LMNAMAPTGPR3 | |
| SCHEMBL16286120 | 0.65 | ALDH1A1 (0.42) | ALDH1A1GAALMNAPAX8MCL1 | |
| SCHEMBL15216878 | 0.62 | PRKCG (0.37) | ALDH1A1GAALMNAPAX8MCL1 | |
| SCHEMBL23520298 | 0.61 | ALDH1A1 (0.36) | NR1H3ALDH1A1GAALMNAPAX8 | |
| SCHEMBL13889162 | 0.61 | GPR3 (0.44) | ALDH1A1GAALMNAKDM4EMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120184547-A1 | METHODS FOR TREATING SCHIZOPHRENIA | AFRAXIS, INC. (US) | 2012-07-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120184547-A1 | METHODS FOR TREATING SCHIZOPHRENIA | PAK2, PAK3, PAK4 | NR1H3 1108/4885ALDH1A1 2121/4885GAA 1293/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.