Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.39 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | NSD2 | O96028 | 1/20 | 0.34 |
| ▸ | APP | P05067 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | SNCA | P37840 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | MPI | P34949 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL27719240 | 0.72 | GPR3 (0.41) | GAAALDH1A1LMNAMCL1PAX8 | |
| SCHEMBL6321054 | 0.70 | GPR3 (0.42) | GAAALDH1A1LMNAMCL1PAX8 | |
| SCHEMBL24150930 | 0.68 | LMNA (0.41) | GAAALDH1A1LMNAMCL1PAX8 | |
| SCHEMBL10345602 | 0.67 | NR1H3 (0.35) | GAAALDH1A1LMNAMCL1PAX8 | |
| SCHEMBL16285651 | 0.67 | ALDH1A1 (0.40) | GAAALDH1A1LMNAMCL1PAX8 | |
| SCHEMBL28926036 | 0.66 | HDAC4 (0.39) | GAAALDH1A1LMNAMCL1PAX8 | |
| SCHEMBL28140243 | 0.66 | HDAC4 (0.36) | GAAALDH1A1LMNAMCL1PAX8 | |
| SCHEMBL8942352 | 0.61 | CRHBP (0.47) | GAAALDH1A1LMNAL3MBTL1MAPT | |
| SCHEMBL15216878 | 0.61 | PRKCG (0.37) | GAAALDH1A1LMNAMCL1PAX8 | |
| SCHEMBL25801904 | 0.61 | HTR2A (0.34) | GAAALDH1A1LMNAMCL1PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117946583-A | Key material for intelligent self-repairing, flame-retardant and light-resistant water-based polyurethane coating | 烟台大学 | 2024-04-30 | — | — | CN | claimed |
| CN-117089275-B | Preparation method of intelligent self-repairing, flame-retardant and light-resistant water-based polyurethane coating | 烟台大学 | 2024-03-12 | — | — | CN | claimed |
| CN-117089275-A | Preparation method of intelligent self-repairing, flame-retardant and light-resistant water-based polyurethane coating | 烟台大学 | 2023-11-21 | — | — | CN | claimed |
| CN-117946583-A | Key material for intelligent self-repairing, flame-retardant and light-resistant water-based polyurethane coating | 烟台大学 | 2024-04-30 | — | — | CN | disclosed |
| CN-117089275-B | Preparation method of intelligent self-repairing, flame-retardant and light-resistant water-based polyurethane coating | 烟台大学 | 2024-03-12 | — | — | CN | disclosed |
| CN-117089275-A | Preparation method of intelligent self-repairing, flame-retardant and light-resistant water-based polyurethane coating | 烟台大学 | 2023-11-21 | — | — | CN | disclosed |