Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 12/20 | 0.45 |
| ▸ | PPARG | P37231 | 10/20 | 0.45 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.45 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.45 |
| ▸ | PPARD | Q03181 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28027915 | 0.87 | LMNA (0.43) | PPARAPPARGMTNR1AMTNR1BGAA | |
| SCHEMBL9116662 | 0.85 | MTNR1A (0.42) | PPARAPPARGMTNR1AMTNR1BPPARD | |
| SCHEMBL7682567 | 0.85 | TDP1 (0.43) | PPARAPPARGMTNR1AMTNR1BPPARD | |
| SCHEMBL5317086 | 0.84 | KMT2A (0.46) | MTNR1AMTNR1BGAATDP1L3MBTL1 | |
| SCHEMBL2464979 | 0.83 | CYP1A2 (0.48) | PPARAPPARGMTNR1AMTNR1BGAA | |
| SCHEMBL8744433 | 0.83 | TSHR (0.46) | GAALMNAALDH1A1TSHRMAPK1 | |
| SCHEMBL7283885 | 0.83 | ALOX15 (0.52) | PPARAPPARGMTNR1AMTNR1BGAA | |
| SCHEMBL10385266 | 0.81 | ALDH1A1 (0.47) | PPARAPPARGMTNR1AMTNR1BGAA | |
| SCHEMBL11493984 | 0.81 | TDP1 (0.54) | MTNR1AMTNR1BTDP1L3MBTL1LMNA | |
| SCHEMBL4303186 | 0.80 | PPARG (0.41) | PPARAPPARGMTNR1AMTNR1BGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0445920-A3 | USE OF ETHOXY PHENOXY ACETIC ACID DERIVATIVES AGAINST DIABETES | — | 1992-10-07 | — | — | EP | disclosed |
| EP-0445920-A2 | Use of ethoxy phenoxy acetic acid derivatives against diabetes | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-09-11 | — | — | EP | disclosed |