SCHEMBL162873

SCHEMBL162873

O=[N+]([O-])NCCc1ccccc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 5/20 0.49
NPC1 O15118 4/20 0.49
RAB9A P51151 4/20 0.49
TAAR1 Q96RJ0 2/20 0.49
ALDH1A1 P00352 4/20 0.48
LMNA P02545 3/20 0.48
MAOA P21397 2/20 0.48
MAOB P27338 2/20 0.48
CYP3A4 P08684 2/20 0.48
ATM Q13315 1/20 0.48
KDM1A O60341 1/20 0.48
CYP1A2 P05177 1/20 0.48
HTR1A P08908 1/20 0.48
ADRA2A P08913 1/20 0.48
CYP2C8 P10632 1/20 0.48
CYP2D6 P10635 1/20 0.48
CYP2C9 P11712 1/20 0.48
IDO1 P14902 1/20 0.48
TSHR P16473 1/20 0.48
NFKB1 P19838 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL5874098 0.98 MAPT (0.48) SMN1; SMN2NPC1RAB9ATAAR1ALDH1A1
Pyridine SCHEMBL20535470 0.89 RAB9A (0.48) SMN1; SMN2NPC1RAB9ATAAR1ALDH1A1
SCHEMBL20592079 0.88 SIGMAR1 (0.55) NPC1RAB9AALDH1A1LMNACYP1A2
SCHEMBL460010 0.78 PTPRF (0.47) SMN1; SMN2CYP3A4CYP1A2CYP2D6CYP2C9
Bromide SCHEMBL17187557 0.77 PTPRF (0.46) SMN1; SMN2CYP3A4CYP1A2CYP2D6CYP2C9
Hydrochloric Acid SCHEMBL6045117 0.77 MAPT (0.46) SMN1; SMN2CYP3A4CYP1A2CYP2D6CYP2C9
Nitric Acid SCHEMBL18329342 0.75 TAAR1 (0.70) SMN1; SMN2NPC1RAB9ATAAR1ALDH1A1
Nitric Acid SCHEMBL10789117 0.73 IDO1 (0.45) SMN1; SMN2ALDH1A1CYP3A4CYP1A2CYP2D6
SCHEMBL28832821 0.73 HDAC2 (0.59) NPC1RAB9AALDH1A1LMNATSHR
SCHEMBL28487383 0.73 MEN1 (0.75) SMN1; SMN2NPC1RAB9ATAAR1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1047 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118806889-A Method for improving adsorption of polysaccharide-protein conjugates and multivalent vaccine formulations obtained therefrom 印度血清研究所私人有限公司 2024-10-22 CN claimed
US-20240293524-A1 MULTIPLE FUNCTIONALIZED noMV CONJUGATES GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2024-09-05 US claimed
US-20230137914-A1 nOMV-ANTIGEN CONJUGATED COMPOUNDS AND USE THEREOF GLAXOSMITHKLINE BIOLOGICALS, S.A. (BE) 2023-05-04 US claimed
EP-4025246-A2 IMMUNOGENIC COMPOSITIONS AGAINST ENTERIC DISEASES AND METHODS FOR ITS PREPARATION THEREOF Serum Institute Of India Private Limited (IN) 2022-07-13 EP claimed
CN-114728053-A Immunogenic compositions against intestinal disease and process for preparing same 印度血清研究所私人有限公司 2022-07-08 CN claimed
US-20220008529-A1 MULTI-FUNCTIONALIZED noMV CONJUGATES GLAXOSMITHKLINE BIOLOGICALS SA (BE) 2022-01-13 US claimed
EP-3799883-A1 NOMV-ANTIGEN CONJUGATED COMPOUNDS AND USE THEREOF GlaxoSmithKline Biologicals S.A. (BE) 2021-04-07 EP claimed
WO-2021044436-A2 IMMUNOGENIC COMPOSITIONS AGAINST ENTERIC DISEASES AND METHODS FOR ITS PREPARATION THEREOF SERUM INSTITUTE OF INDIA PRIVATE LIMITED (IN) 2021-03-11 WO claimed
EP-3664837-A1 MULTI-FUNCTIONALIZED nOMV CONJUGATES GlaxoSmithKline Biologicals S.A. (BE) 2020-06-17 EP claimed
EP-3544637-A1 nOMV-ANTIGEN CONJUGATES AND USE THEREOF GlaxoSmithKline Biologicals S.A. (BE) 2019-10-02 EP claimed
WO-2018096013-A1 nOMV-ANTIGEN CONJUGATES AND USE THEREOF GLAXOSMITHKLINE BIOLOGICALS S.A. (BE) 2018-05-31 WO claimed
CN-104519910-B Adjuvanted formulations of streptococcus pneumoniae antigens 诺华股份有限公司 2017-05-03 CN claimed
WO-2017067964-A1 P. AERUGINOSA PCRV-LINKED ANTIGEN VACCINES GLAXOSMITHKLINE BIOLOGICALS S.A. (BE) 2017-04-27 WO claimed
CN-104519910-A Adjuvanted formulations of streptococcus pneumoniae antigens NOVARTIS AG 2015-04-15 CN claimed
EP-2822586-A1 ADJUVANTED FORMULATIONS OF STREPTOCOCCUS PNEUMONIAE ANTIGENS Novartis AG (CH) 2015-01-14 EP claimed
WO-2013131983-A1 ADJUVANTED FORMULATIONS OF STREPTOCOCCUS PNEUMONIAE ANTIGENS NOVARTIS AG (CH) 2013-09-12 WO claimed
EP-2254890-A1 PROCESS FOR THE DIASTEREOISOMERIC RESOLUTION OF 5-METHYLTETRAHYDROFOLIC ACID Gnosis S.p.A. (IT) 2010-12-01 EP claimed
WO-2009103333-A1 PROCESS FOR THE DIASTEREOISOMERIC RESOLUTION OF 5-METHYLTETRAHYDROFOLIC ACID GNOSIS S.P.A. (IT) 2009-08-27 WO claimed
EP-1476197-A2 SYNTHESIS OF LIPOPOLYSACCHARIDE-PROTEIN CONJUGATE VACCINES VIA THE LIPID A REGION FOLLOWING REMOVAL OF THE GLYCOSIDIC PHOSPHATE RESIDUE NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2004-11-17 EP claimed
WO-2003070282-A2 SYNTHESIS OF LIPOPOLYSACCHARIDE-PROTEIN CONJUGATE VACCINES VIA THE LIPID A REGION FOLLOWING REMOVAL OF THE GLYCOSIDIC PHOSPHATE RESIDUE NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2003-08-28 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230137914-A1 nOMV-ANTIGEN CONJUGATED COMPOUNDS AND USE THEREOF VAPB, CD14, CHMP4B SMN1; SMN2 4307/4885NPC1 380/4885RAB9A 297/4885
US-20240293524-A1 MULTIPLE FUNCTIONALIZED noMV CONJUGATES CD14, VAPB, CHMP4B SMN1; SMN2 4171/4885NPC1 384/4885RAB9A 290/4885
US-20220008529-A1 MULTI-FUNCTIONALIZED noMV CONJUGATES CD14, CHMP4B, VAPB SMN1; SMN2 4243/4885NPC1 390/4885RAB9A 337/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.