SCHEMBL16289502

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL15083124	1.00	CYP1A2 (0.36)	CYP1A2GAACYP2D6CYP2C9CYP2C19
	SCHEMBL15083078	0.91	CYP1A2 (0.36)	CYP1A2GAACYP2D6CYP2C9CYP2C19
	SCHEMBL16288835	0.91	CYP1A2 (0.36)	CYP1A2GAACYP2D6CYP2C9CYP2C19
	SCHEMBL16289202	0.86	CASP1 (0.33)	CASP1CTSLCTSSCTSBKMT2A
	SCHEMBL16289204	0.86	CASP1 (0.33)	CASP1CTSLCTSSCTSBKMT2A
	SCHEMBL21895862	0.86	CASP1 (0.40)	CASP1CTSLCTSSFAAH
	SCHEMBL28362248	0.86	CASP1 (0.40)	CASP1CTSLCTSSFAAH
	SCHEMBL21895861	0.86	CTSS (0.43)	CASP1CTSLCTSSCTSBFAAH
	SCHEMBL21895863	0.86	CTSS (0.43)	CASP1CTSLCTSSCTSBFAAH
	SCHEMBL16288644	0.84	NAALAD2 (0.42)	ACEFAAH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.