Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 3/20 | 0.43 |
| ▸ | ANPEP | P15144 | 1/20 | 0.43 |
| ▸ | ECE1 | P42892 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.43 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.43 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.43 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.43 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1444015 | 0.84 | ALOX15 (0.41) | ALDH1A1MEN1TSHRKMT2ALMNA | |
| SCHEMBL9478955 | 0.83 | KMT2A (0.36) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL8125303 | 0.79 | KMT2A (0.34) | ALDH1A1MEN1KMT2ALMNASMN1; SMN2 | |
| SCHEMBL1903196 | 0.79 | KMT2A (0.34) | ALDH1A1MEN1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL28070090 | 0.76 | EPHX2 (0.50) | CA2CA1LMNA | |
| SCHEMBL8119388 | 0.75 | PGR (0.40) | ALDH1A1MEN1TSHRKMT2ASMN1; SMN2 | |
| SCHEMBL15527899 | 0.75 | HPGD (0.34) | ALDH1A1MEN1TSHRKMT2AMME | |
| SCHEMBL295086 | 0.74 | GAA (0.42) | ALDH1A1TSHRHDAC8HDAC6SMN1; SMN2 | |
| SCHEMBL11111257 | 0.74 | ALDH1A1 (0.56) | LTA4HALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL11111255 | 0.74 | ALDH1A1 (0.56) | LTA4HALDH1A1MEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014200885-A1 | PDE10a INHIBITORS FOR THE TREATMENT OF TYPE II DIABETES | JANSSEN PHARMACEUTICA NV (BE) | 2014-12-18 | — | — | WO | claimed |
| WO-2014200885-A1 | PDE10a INHIBITORS FOR THE TREATMENT OF TYPE II DIABETES | JANSSEN PHARMACEUTICA NV (BE) | 2014-12-18 | — | — | WO | disclosed |