Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.50 |
| ▸ | NAMPT | P43490 | 2/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.43 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | JAK2 | O60674 | 1/20 | 0.38 |
| ▸ | JAK1 | P23458 | 1/20 | 0.38 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | MMP2 | P08253 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | IDO1 | P14902 | 3/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1444015 | 0.80 | ALOX15 (0.41) | LMNATDP1 | |
| SCHEMBL9478955 | 0.79 | KMT2A (0.36) | NPC1RAB9ALMNA | |
| SCHEMBL16294271 | 0.76 | LTA4H (0.47) | LMNACA1CA2 | |
| SCHEMBL1903196 | 0.75 | KMT2A (0.34) | NPC1RAB9A | |
| SCHEMBL8125303 | 0.75 | KMT2A (0.34) | NPC1RAB9ALMNA | |
| SCHEMBL3764748 | 0.74 | SSTR4 (0.43) | NPC1RAB9ALMNA | |
| SCHEMBL8118163 | 0.74 | ALDH1A1 (0.40) | NPC1LMNA | |
| SCHEMBL8131986 | 0.72 | ALDH1A1 (0.42) | NPC1RAB9ALMNA | |
| SCHEMBL1990596 | 0.72 | NPC1 (0.49) | EPHX2NPC1RAB9ASMYD3LMNA | |
| SCHEMBL8119388 | 0.72 | PGR (0.40) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105745201-B | 1-aryl-3-alkylpyrazole insecticides | FMC公司 | 2019-08-20 | — | — | CN | disclosed |
| CN-109890807-A | The bicyclic azoles pesticide of heterocyclic substituted | FMC 公司 | 2019-06-14 | — | — | CN | disclosed |
| CN-105745201-A | 1-aryl-3-alkylpyrazole insecticides | 纳幕尔杜邦公司 | 2016-07-06 | — | — | CN | disclosed |