Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.51 |
| ▸ | RAB9A | P51151 | 4/20 | 0.51 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Pibecarb SCHEMBL2109461 | 0.84 | NPC1 (0.56) | NPC1RAB9AHPGDL3MBTL1TSHR | |
| SCHEMBL28050529 | 0.82 | NPC1 (0.50) | NPC1RAB9AHPGDL3MBTL1TSHR | |
| SCHEMBL846938 | 0.76 | ALDH1A1 (0.56) | NPC1RAB9AHPGDL3MBTL1LMNA | |
| SCHEMBL7720386 | 0.75 | NPC1 (0.53) | NPC1RAB9AHPGDL3MBTL1TSHR | |
| SCHEMBL10875576 | 0.75 | NPC1 (0.53) | NPC1RAB9AHPGDL3MBTL1TSHR | |
| SCHEMBL1907159 | 0.74 | NPC1 (0.61) | NPC1RAB9AHPGDL3MBTL1TSHR | |
| SCHEMBL291698 | 0.74 | L3MBTL1 (0.59) | NPC1RAB9AHPGDL3MBTL1TSHR | |
| SCHEMBL291697 | 0.74 | L3MBTL1 (0.59) | NPC1RAB9AHPGDL3MBTL1TSHR | |
| SCHEMBL10809629 | 0.74 | L3MBTL1 (0.59) | NPC1RAB9AHPGDL3MBTL1TSHR | |
| SCHEMBL17636576 | 0.74 | TSHR (0.36) | TSHRCYP2C19SMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8362159-B2 | Degradable biocompatible block copolymer | EIDGENOSSISCHE TECHNISCHE HOCHSCHULE ZURICH (CH) | 2013-01-29 | — | — | US | disclosed |
| US-20110093066-A1 | Degradable Biocompatible Block Copolymer | EIDGENOSSISCHE TECHNISCHE HOCHSCHULE ZURICH (CH) | 2011-04-21 | — | — | US | disclosed |
| US-20060178477-A1 | Degradable biocompatible block copolymer | EIDGENOSSISCHE TECHNISCHE HOCHSCHULE ZURICH (CH) | 2006-08-10 | — | — | US | disclosed |