Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 14/20 | 0.71 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 9/20 | 0.67 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | HPGD | P15428 | 8/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | FNTA | P49354 | 1/20 | 0.52 |
| ▸ | FNTB | P49356 | 1/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | RET | P07949 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4535362 | 0.97 | KDM4E (0.71) | KDM4EHSD17B10ALDH1A1ADORA2ASMN1; SMN2 | |
| SCHEMBL16295274 | 0.86 | KDM4E (0.56) | KDM4EHSD17B10ALDH1A1ADORA2ASMN1; SMN2 | |
| SCHEMBL17351540 | 0.83 | KDM4E (0.71) | KDM4EHSD17B10ALDH1A1ADORA2ASMN1; SMN2 | |
| SCHEMBL6252358 | 0.83 | KDM4E (1.00) | KDM4EHSD17B10ALDH1A1ADORA2ASMN1; SMN2 | |
| SCHEMBL16294362 | 0.83 | KDM4E (0.70) | KDM4EHSD17B10ALDH1A1ADORA2ASMN1; SMN2 | |
| SCHEMBL17351373 | 0.82 | KDM4E (0.97) | KDM4EHSD17B10ALDH1A1ADORA2ASMN1; SMN2 | |
| SCHEMBL1177057 | 0.80 | KDM4E (1.00) | KDM4EHSD17B10ALDH1A1ADORA2ASMN1; SMN2 | |
| SCHEMBL1177499 | 0.80 | KDM4E (0.75) | KDM4EHSD17B10ALDH1A1ADORA2ASMN1; SMN2 | |
| SCHEMBL1177695 | 0.79 | KDM4E (0.69) | KDM4EHSD17B10ALDH1A1ADORA2ASMN1; SMN2 | |
| SCHEMBL4535360 | 0.79 | KDM4E (0.64) | KDM4EHSD17B10ALDH1A1ADORA2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11375716-B2 | Acetyl-CoA carboxylase modulators | MONSANTO TECHNOLOGY LLC (US) | 2022-07-05 | — | — | US | disclosed |
| US-20200214289-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2020-07-09 | — | — | US | disclosed |
| US-10548313-B2 | Acetyl-CoA carboxylase modulators | MONSANTO TECHNOLOGY LLC (US) | 2020-02-04 | — | — | US | disclosed |
| US-20180070589-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2018-03-15 | — | — | US | disclosed |
| US-9844218-B2 | Acetyl-CoA carboxylase modulators | MONSANTO TECHNOLOGY LLC (US) | 2017-12-19 | — | — | US | disclosed |
| US-20160130229-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2016-05-12 | — | — | US | disclosed |
| WO-2014201326-A1 | ACETYL-COA CARBOXYLASE MODULATORS | MONSANTO TECHNOLOGY LLC (US) | 2014-12-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160130229-A1 | ACETYL-COA CARBOXYLASE MODULATORS | ACACA, ACACB, ACAT2 | KDM4E 1598/4885HSD17B10 105/4885ALDH1A1 1039/4885 |
| US-11375716-B2 | Acetyl-CoA carboxylase modulators | ACACA, ACACB, ACAT2 | KDM4E 1598/4885HSD17B10 105/4885ALDH1A1 1039/4885 |
| US-10548313-B2 | Acetyl-CoA carboxylase modulators | ACACA, ACACB, ACAT2 | KDM4E 1598/4885HSD17B10 105/4885ALDH1A1 1039/4885 |
| US-20200214289-A1 | ACETYL-COA CARBOXYLASE MODULATORS | ACACA, ACACB, ACAT2 | KDM4E 1598/4885HSD17B10 105/4885ALDH1A1 1039/4885 |
| US-20180070589-A1 | ACETYL-COA CARBOXYLASE MODULATORS | ACACA, ACACB, ACAT2 | KDM4E 1598/4885HSD17B10 105/4885ALDH1A1 1039/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.