Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.36 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | CXCL8 | P10145 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9725165 | 0.83 | SMN1; SMN2 (0.44) | LMNAKMT2AALDH1A1RECQLSMN1; SMN2 | |
| SCHEMBL8810182 | 0.81 | LMNA (0.63) | LMNAL3MBTL1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL3996276 | 0.80 | SMN1; SMN2 (0.53) | L3MBTL1KMT2AALDH1A1RECQLSMN1; SMN2 | |
| SCHEMBL7020569 | 0.76 | ALDH1A1 (0.37) | LMNAL3MBTL1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL1665108 | 0.76 | NPC1 (0.47) | ALDH1A1SMN1; SMN2 | |
| SCHEMBL8669623 | 0.76 | HSD17B10 (0.50) | LMNAKMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL97872 | 0.76 | KEAP1 (0.48) | LMNAKEAP1L3MBTL1KMT2AALDH1A1 | |
| SCHEMBL97108 | 0.76 | HSD17B10 (0.48) | L3MBTL1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL3754787 | 0.75 | SMN1; SMN2 (0.63) | LMNAKMT2ASMN1; SMN2 | |
| SCHEMBL4202296 | 0.74 | ACP1 (0.69) | ACP1LMNAKEAP1L3MBTL1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014200885-A1 | PDE10a INHIBITORS FOR THE TREATMENT OF TYPE II DIABETES | JANSSEN PHARMACEUTICA NV (BE) | 2014-12-18 | — | — | WO | claimed |