SCHEMBL8810182

SCHEMBL8810182

Cc1ccc(S(=O)(=O)NC(=O)Nc2[c]cccc2)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.63
KMT2A Q03164 2/20 0.58
L3MBTL1 Q9Y468 1/20 0.58
TP53 P04637 1/20 0.53
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA2 P00918 1/20 0.53
CA4 P22748 1/20 0.53
CA6 P23280 1/20 0.53
CA5A P35218 1/20 0.53
CA7 P43166 1/20 0.53
CA9 Q16790 1/20 0.53
CA13 Q8N1Q1 1/20 0.53
CA14 Q9ULX7 1/20 0.53
NLRP3 Q96P20 2/20 0.53
KDM4E B2RXH2 1/20 0.53
ALDH1A1 P00352 2/20 0.51
PPARG P37231 1/20 0.51
RAB9A P51151 1/20 0.51
RXFP1 Q9HBX9 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16295404 0.81 ACP1 (0.40) LMNAKMT2AL3MBTL1ALDH1A1SMN1; SMN2
SCHEMBL8724554 0.79 L3MBTL1 (0.81) LMNAKMT2AL3MBTL1TP53CA12
SCHEMBL3336206 0.79 CA2 (0.57) LMNAKMT2AL3MBTL1CA12CA1
SCHEMBL27885 0.78 LMNA (1.00) LMNAKMT2AL3MBTL1TP53CA12
SCHEMBL9182658 0.77 LMNA (0.76) LMNAKMT2AL3MBTL1TP53CA12
SCHEMBL5184740 0.77 LMNA (0.69) LMNAKMT2AL3MBTL1TP53CA12
SCHEMBL1928662 0.76 CA12 (0.85) LMNAKMT2AL3MBTL1TP53CA12
SCHEMBL6243996 0.76 CA12 (0.85) LMNAKMT2AL3MBTL1TP53CA12
SCHEMBL5185904 0.75 L3MBTL1 (0.74) LMNAKMT2AL3MBTL1TP53CA12
SCHEMBL8418021 0.75 L3MBTL1 (0.70) LMNAKMT2AL3MBTL1TP53CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-9011632-A None JP disclosed
JP-H0911632-A THERMAL RECORDING MATERIAL NEW OJI PAPER CO LTD 1997-01-14 JP disclosed