Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.57 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | TOP1 | P11387 | 3/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.45 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 3/20 | 0.44 |
| ▸ | PPARG | P37231 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | PPARD | Q03181 | 3/20 | 0.42 |
| ▸ | PPARA | Q07869 | 3/20 | 0.42 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.42 |
| ▸ | F7 | P08709 | 2/20 | 0.42 |
| ▸ | F3 | P13726 | 2/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.42 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21958790 | 0.81 | HTT (0.46) | HTTPKMPOLBTOP1BACE1 | |
| SCHEMBL16306922 | 0.80 | HTT (0.67) | HTTPKMPOLBBACE1HSD17B1 | |
| SCHEMBL16295827 | 0.80 | HTT (0.67) | HTTPKMPOLBBACE1HSD17B1 | |
| SCHEMBL16295828 | 0.80 | HTT (0.67) | HTTPKMPOLBBACE1HSD17B1 | |
| 3-Prenyl-4-Hydroxyacetophenone SCHEMBL4120403 | 0.73 | HTT (1.00) | HTTPKMPOLBBACE1HSD17B1 | |
| SCHEMBL1092424 | 0.73 | HTT (0.71) | HTTPKMPOLBBACE1HSD17B1 | |
| SCHEMBL11125937 | 0.73 | PKM (0.68) | HTTPKMPOLBHSD17B10HSD17B1 | |
| SCHEMBL10306496 | 0.72 | BACE1 (0.56) | HTTPKMPOLBBACE1ALDH1A1 | |
| SCHEMBL8454522 | 0.72 | BACE1 (0.56) | HTTPKMPOLBBACE1ALDH1A1 | |
| SCHEMBL24075566 | 0.71 | HTT (0.76) | HTTPKMPOLBBACE1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200123197-A1 | METHOD OF MAKING A CROSS METATHESIS PRODUCT | NATIONAL SCIENCE FOUNDATION | 2020-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200123197-A1 | METHOD OF MAKING A CROSS METATHESIS PRODUCT | DUOX2, DUOX1, RNF168 | HTT 4420/4885PKM 3354/4885POLB 392/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.