Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TET2 | Q6N021 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.33 |
| ▸ | SI | P14410 | 1/20 | 0.33 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.33 |
| ▸ | BIRC2 | Q13490 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12388730 | 0.76 | TET2 (0.54) | TET2RECQLALDH1A1LMNATSHR | |
| SCHEMBL4813094 | 0.72 | TSHR (0.52) | TET2RECQLALDH1A1LMNATSHR | |
| SCHEMBL19112483 | 0.71 | TET2 (0.48) | TET2RECQLALDH1A1LMNATSHR | |
| SCHEMBL28972402 | 0.71 | LMNA (0.56) | RECQLALDH1A1LMNATSHRKDM4E | |
| SCHEMBL14440671 | 0.70 | TET2 (0.52) | TET2RECQLALDH1A1TSHRHSD17B10 | |
| SCHEMBL9477697 | 0.69 | TET2 (0.47) | TET2RECQLALDH1A1LMNATSHR | |
| SCHEMBL10266048 | 0.69 | TET2 (0.47) | TET2RECQLALDH1A1LMNATSHR | |
| SCHEMBL7889565 | 0.69 | TET2 (0.47) | TET2RECQLALDH1A1LMNATSHR | |
| SCHEMBL22753025 | 0.69 | POLB (0.37) | ALDH1A1TSHRGAACA12CA2 | |
| SCHEMBL7826416 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8088923-B2 | Cyclic-fused beta-lactones and their synthesis | THE TEXAS A&M UNIVERSITY SYSTEM (US) | 2012-01-03 | — | — | US | disclosed |
| US-20090062547-A1 | CYCLIC-FUSED BETA-LACTONES AND THEIR SYNTHESIS | THE TEXAS A&M UNIVERSITY SYSTEM | 2009-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090062547-A1 | CYCLIC-FUSED BETA-LACTONES AND THEIR SYNTHESIS | COASY, FASN, OTUB1 | TET2 2380/4885RECQL 3474/4885ALDH1A1 1236/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.