Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGAM1 | P18669 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 3/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
| ▸ | RAB9A | P51151 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13868655 | 0.93 | PDK2 (0.34) | PGAM1KMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL10293306 | 0.93 | PDK2 (0.34) | PGAM1KMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL10292671 | 0.89 | AVPR2 (0.33) | PGAM1KMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL10261681 | 0.89 | PDK2 (0.34) | PGAM1KMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL16301036 | 0.89 | ALDH1A1 (0.33) | PGAM1KMT2AALDH1A1MEN1MAPT | |
| SCHEMBL10261395 | 0.89 | AVPR1A (0.36) | PGAM1KMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL10267872 | 0.87 | MEN1 (0.35) | KMT2AALDH1A1MEN1KDM4ECYP3A4 | |
| SCHEMBL10292851 | 0.86 | PDK2 (0.35) | PGAM1KMT2AALDH1A1MEN1KDM4E | |
| SCHEMBL13868706 | 0.86 | ALDH1A1 (0.34) | KMT2AALDH1A1MEN1KDM4ECYP3A4 | |
| SCHEMBL10262914 | 0.85 | TTR (0.34) | CYP3A4HPGDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8691120-B2 | Chromene compound | TOKUYAMA CORPORATION (JP) | 2014-04-08 | — | — | US | disclosed |
| US-20120170098-A1 | CHROMENE COMPOUND | TOKUYAMA CORPORATION (JP) | 2012-07-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120170098-A1 | CHROMENE COMPOUND | CRY2, CRY1, SUN2 | PGAM1 2923/4885KMT2A 2494/4885ALDH1A1 2266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.