SCHEMBL163023

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL160832	0.86	SMN1; SMN2 (0.41)	NPC1HPGDHDAC1ALDH1A1L3MBTL1
	SCHEMBL162785	0.83	HTT (0.46)	NPC1HPGDHDAC1L3MBTL1SMN1; SMN2
	SCHEMBL162901	0.83	KMT2A (0.44)	NPC1HPGDALDH1A1SMN1; SMN2RAB9A
	SCHEMBL30567660	0.82	HDAC3 (0.46)	NPC1HPGDHDAC1ALDH1A1L3MBTL1
	SCHEMBL163024	0.82	NPC1 (0.37)	NPC1HPGDIKBKBCHUKHDAC1
	SCHEMBL2422284	0.81	PRKCZ (0.38)	NPC1HPGDIKBKBCHUKHDAC1
	SCHEMBL163473	0.79	HPGD (0.40)	NPC1HPGDIKBKBCHUKHDAC6
	SCHEMBL162851	0.77	MEN1 (0.43)	NPC1HPGDALDH1A1L3MBTL1SMN1; SMN2
	SCHEMBL18649490	0.77	HSD17B10 (0.50)	NPC1HPGDALDH1A1SMN1; SMN2RAB9A
	SCHEMBL161611	0.75	ALDH1A1 (0.46)	NPC1HPGDALDH1A1L3MBTL1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.