Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.57 |
| ▸ | RAB9A | P51151 | 4/20 | 0.57 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.51 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.51 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.49 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.48 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.48 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.42 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8939884 | 0.86 | KCNH2 (0.47) | NPC1RAB9APDGFRBPDGFRAACMSD | |
| SCHEMBL5268060 | 0.81 | NCOA1 (0.47) | NPC1RAB9APDGFRBPDGFRACYP1A2 | |
| SCHEMBL10489436 | 0.80 | NPC1 (0.53) | NPC1RAB9AACMSDPTGS2KCNH2 | |
| SCHEMBL11659183 | 0.79 | NPC1 (0.51) | NPC1RAB9AACMSDPTGS2KCNH2 | |
| SCHEMBL11659189 | 0.79 | NPC1 (0.51) | NPC1RAB9AACMSDPTGS2KCNH2 | |
| SCHEMBL31240857 | 0.77 | PDGFRB (0.46) | NPC1RAB9APDGFRBPDGFRACYP1A2 | |
| SCHEMBL1257312 | 0.77 | RAB9A (0.50) | NPC1RAB9ACYP1A2CYP3A4CYP2C9 | |
| SCHEMBL19737305 | 0.76 | GSTP1 (0.53) | NPC1RAB9AHSD17B1HSD17B2GSTP1 | |
| SCHEMBL5584786 | 0.76 | NISCH (0.48) | NPC1RAB9AHSD17B1HSD17B2GSTP1 | |
| SCHEMBL18905380 | 0.76 | ACMSD (0.44) | NPC1RAB9APDGFRBPDGFRAACMSD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210122978-A1 | Liquid Crystals Comprising Cyclopentane Groups | VVI BRIGHT CHINA LTD (CN) | 2021-04-29 | — | — | US | disclosed |
| US-20210122978-A1 | Liquid Crystals Comprising Cyclopentane Groups | VVI BRIGHT CHINA LTD (CN) | 2021-04-29 | — | — | US | disclosed |
| US-10745617-B2 | Liquid crystals comprising cyclopentane groups | VVI BRIGHT CHINA LTD (CN) | 2020-08-18 | — | — | US | disclosed |
| US-10745617-B2 | Liquid crystals comprising cyclopentane groups | VVI BRIGHT CHINA LTD (CN) | 2020-08-18 | — | — | US | disclosed |
| US-20180163131-A1 | LIQUID CRYSTALS COMPRISING CYCLOPENTANE GROUPS | VVI BRIGHT, INC. | 2018-06-14 | — | — | US | disclosed |
| US-20180163131-A1 | LIQUID CRYSTALS COMPRISING CYCLOPENTANE GROUPS | VVI BRIGHT, INC. | 2018-06-14 | — | — | US | disclosed |
| US-9822303-B2 | Liquid crystals comprising cyclopentane groups | VVI BRIGHT CHINA LTD (CN) | 2017-11-21 | — | — | US | disclosed |
| US-9822303-B2 | Liquid crystals comprising cyclopentane groups | VVI BRIGHT CHINA LTD (CN) | 2017-11-21 | — | — | US | disclosed |
| US-20160237348-A1 | LIQUID CRYSTALS COMPRISING CYCLOPENTANE GROUPS | VVI BRIGHT, INC. | 2016-08-18 | — | — | US | disclosed |
| US-20160237348-A1 | LIQUID CRYSTALS COMPRISING CYCLOPENTANE GROUPS | VVI BRIGHT, INC. | 2016-08-18 | — | — | US | disclosed |
| US-8801966-B2 | Liquid crystals comprising cyclopentane groups | VVI BRIGHT CHINA LTD. (CN) | 2014-08-12 | — | — | US | disclosed |
| US-8801966-B2 | Liquid crystals comprising cyclopentane groups | VVI BRIGHT CHINA LTD. (CN) | 2014-08-12 | — | — | US | disclosed |
| CN-101978024-B | Liquid crystals comprising cyclopentane groups | JINGMEISHENG OPTOELECTRIC MATERIAL NANJING CO LTD | 2014-05-07 | — | — | CN | disclosed |
| CN-103320141-A | Liquid crystals comprising cyclopentane groups | VVI BRIGHT INC | 2013-09-25 | — | — | CN | disclosed |
| CN-103319306-A | Liquid crystals comprising cyclopentane groups | VVI BRIGHT INC | 2013-09-25 | — | — | CN | disclosed |
| US-20110089374-A1 | Liquid Crystals Comprising Cyclopentane Groups | VVI BRIGHT, INC. (US) | 2011-04-21 | — | — | US | disclosed |
| US-20110089374-A1 | Liquid Crystals Comprising Cyclopentane Groups | VVI BRIGHT, INC. (US) | 2011-04-21 | — | — | US | disclosed |
| CN-101978024-A | Liquid crystals comprising cyclopentane groups | VVI BRIGHT INC | 2011-02-16 | — | — | CN | disclosed |
| WO-2009100204-A1 | LIQUID CRYSTALS COMPRISING CYCLOPENTANE GROUPS | VVI BRIGHT, INC. (US) | 2009-08-13 | — | — | WO | disclosed |
| WO-2009100204-A1 | LIQUID CRYSTALS COMPRISING CYCLOPENTANE GROUPS | VVI BRIGHT, INC. (US) | 2009-08-13 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210122978-A1 | Liquid Crystals Comprising Cyclopentane Groups | CXCR5, CCL5, ELOC | NPC1 1149/4885RAB9A 3187/4885HSD17B1 1264/4885 |
| US-10745617-B2 | Liquid crystals comprising cyclopentane groups | CXCR5, CCL5, ELOC | NPC1 1149/4885RAB9A 3187/4885HSD17B1 1264/4885 |
| US-20180163131-A1 | LIQUID CRYSTALS COMPRISING CYCLOPENTANE GROUPS | CXCR5, CCL5, ELOC | NPC1 1149/4885RAB9A 3187/4885HSD17B1 1264/4885 |
| US-20110089374-A1 | Liquid Crystals Comprising Cyclopentane Groups | CXCR5, CCL5, ELOC | NPC1 1149/4885RAB9A 3187/4885HSD17B1 1264/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.