Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 4/20 | 0.71 |
| ▸ | CA1 | P00915 | 3/20 | 0.71 |
| ▸ | CA5A | P35218 | 3/20 | 0.71 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.71 |
| ▸ | FLT3 | P36888 | 2/20 | 0.63 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.60 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.60 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.59 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.59 |
| ▸ | CA12 | O43570 | 3/20 | 0.58 |
| ▸ | CA9 | Q16790 | 3/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.56 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | AURKA | O14965 | 1/20 | 0.48 |
| ▸ | STIM1 | Q13586 | 2/20 | 0.48 |
| ▸ | ORAI1 | Q96D31 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31473217 | 1.00 | CA2 (0.71) | CA2CA1CA5ACA5BFLT3 | |
| SCHEMBL15040972 | 0.91 | CA2 (0.67) | CA2CA1CA5ACA5BFLT3 | |
| SCHEMBL14226896 | 0.89 | KEAP1 (0.71) | CA2CA1CA5ACA5BFLT3 | |
| SCHEMBL28148270 | 0.87 | CA2 (0.57) | CA2CA1CA5ACA5BFLT3 | |
| SCHEMBL12522541 | 0.85 | FLT3 (0.73) | CA2CA1CA5ACA5BFLT3 | |
| SCHEMBL31473225 | 0.84 | KEAP1 (0.62) | CA2CA1CA5ACA5BFLT3 | |
| SCHEMBL13453289 | 0.83 | FLT3 (0.81) | CA2CA1CA5ACA5BFLT3 | |
| SCHEMBL26803794 | 0.83 | STIM1 (0.69) | CA2CA1CA5ACA5BFLT3 | |
| SCHEMBL31473222 | 0.80 | KEAP1 (0.64) | CA2CA1CA5ACA5BFLT3 | |
| SCHEMBL31158277 | 0.79 | FLT3 (0.58) | CA2CA1CA5ACA5BFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117342969-A | (E) -alpha, beta-unsaturated amide derivative, preparation method and application thereof | 昆明理工大学 | 2024-01-05 | — | — | CN | disclosed |
| US-20230348404-A1 | BIPHENYL COMPOUNDS AS SOCE MODULATORS, COMPOSITIONS AND USES THEREOF | UNIVERSITÀ DEGLI STUDI DEL PIEMONTE ORIENTALE "AMEDEO AVOGADRO" (IT) | 2023-11-02 | — | — | US | disclosed |
| US-20140371825-A1 | ORGANIC METAL COMPLEXES | UDC IRELAND LIMITED (IE) | 2014-12-18 | — | — | US | disclosed |
| US-20140371825-A1 | ORGANIC METAL COMPLEXES | UDC IRELAND LIMITED (IE) | 2014-12-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230348404-A1 | BIPHENYL COMPOUNDS AS SOCE MODULATORS, COMPOSITIONS AND USES THEREOF | ORAI1, SARAF, STIM1 | CA2 68/4885CA1 798/4885CA5A 424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.