Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 3/20 | 0.67 |
| ▸ | CA1 | P00915 | 2/20 | 0.67 |
| ▸ | CA5A | P35218 | 2/20 | 0.67 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.67 |
| ▸ | KEAP1 | Q14145 | 3/20 | 0.62 |
| ▸ | NFE2L2 | Q16236 | 3/20 | 0.62 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.56 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.56 |
| ▸ | CA12 | O43570 | 2/20 | 0.55 |
| ▸ | CA9 | Q16790 | 2/20 | 0.55 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.54 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.54 |
| ▸ | CDC7 | O00311 | 1/20 | 0.52 |
| ▸ | FLT3 | P36888 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14226896 | 0.92 | KEAP1 (0.71) | CA2CA1CA5ACA5BKEAP1 | |
| SCHEMBL16307343 | 0.91 | CA2 (0.71) | CA2CA1CA5ACA5BKEAP1 | |
| SCHEMBL31473217 | 0.91 | CA2 (0.71) | CA2CA1CA5ACA5BKEAP1 | |
| SCHEMBL1119554 | 0.83 | PTGS2 (0.66) | CA2CA1CA5ACA5BKEAP1 | |
| SCHEMBL31473222 | 0.82 | KEAP1 (0.64) | CA2CA1CA5ACA5BKEAP1 | |
| SCHEMBL12522541 | 0.82 | FLT3 (0.73) | CA2CA1CA5ACA5BKEAP1 | |
| SCHEMBL12420373 | 0.82 | FLT3 (0.69) | CA2CA1CA5ACA5BKEAP1 | |
| SCHEMBL31158277 | 0.82 | FLT3 (0.58) | CA2CA1CA5ACA5BKEAP1 | |
| SCHEMBL28148270 | 0.81 | CA2 (0.57) | CA2CA1CA5ACA5BKEAP1 | |
| Bromide SCHEMBL6256547 | 0.81 | PTGS2 (0.64) | CA2CA1CA5ACA5BKEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10403833-B2 | Organic metal complexes | MERCK PATENT GMBH (DE) | 2019-09-03 | — | — | US | disclosed |
| EP-2856528-B1 | METAL COMPLEXES COMPRISING CONDENSED HETEROAROMATIC RINGS | MERCK PATENT GMBH (DE) | 2019-07-03 | — | — | EP | disclosed |
| US-9879177-B2 | Metal complexes comprising condensed heteroaromatic rings | MERCK PATENT GMBH (DE) | 2018-01-30 | — | — | US | disclosed |
| US-9879177-B2 | Metal complexes comprising condensed heteroaromatic rings | MERCK PATENT GMBH (DE) | 2018-01-30 | — | — | US | disclosed |
| US-20170317298-A1 | ORGANIC METAL COMPLEXES | UDC IRELAND LIMITED (IE) | 2017-11-02 | — | — | US | disclosed |
| US-20170317298-A1 | ORGANIC METAL COMPLEXES | UDC IRELAND LIMITED (IE) | 2017-11-02 | — | — | US | disclosed |
| US-9748502-B2 | Organic metal complexes | MERCK PATENT GMBH (DE) | 2017-08-29 | — | — | US | disclosed |
| US-9748502-B2 | Organic metal complexes | MERCK PATENT GMBH (DE) | 2017-08-29 | — | — | US | disclosed |
| EP-2791275-B1 | ORGANIC SENSITIZERS FOR UP-CONVERSION | MERCK PATENT GMBH (DE) | 2017-05-31 | — | — | EP | disclosed |
| EP-2797940-B1 | METAL COMPLEXES COMPRISING 1,2,3-TRIAZOLES | MERCK PATENT GMBH (DE) | 2016-02-24 | — | — | EP | disclosed |
| US-20140371825-A1 | ORGANIC METAL COMPLEXES | UDC IRELAND LIMITED (IE) | 2014-12-18 | — | — | US | disclosed |
| US-20140371825-A1 | ORGANIC METAL COMPLEXES | UDC IRELAND LIMITED (IE) | 2014-12-18 | — | — | US | disclosed |
| US-20140358198-A1 | ORGANIC SENSITIZERS FOR UP-CONVERSION | MERCK PATENT GMBH (DE) | 2014-12-04 | — | — | US | disclosed |
| US-20140358198-A1 | ORGANIC SENSITIZERS FOR UP-CONVERSION | MERCK PATENT GMBH (DE) | 2014-12-04 | — | — | US | disclosed |
| US-20140350642-A1 | Metal Complexes Comprising 1,2,3-Triazoles | MERCK PATENT GMBH (DE) | 2014-11-27 | — | — | US | disclosed |
| US-20140350642-A1 | Metal Complexes Comprising 1,2,3-Triazoles | MERCK PATENT GMBH (DE) | 2014-11-27 | — | — | US | disclosed |
| WO-2013174471-A1 | METAL COMPLEXES COMPRISING CONDENSED HETEROAROMATIC RINGS | MERCK PATENT GMBH (DE) | 2013-11-28 | — | — | WO | disclosed |
| WO-2013107487-A1 | ORGANIC METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2013-07-25 | — | — | WO | disclosed |
| WO-2013097920-A1 | METAL COMPLEXES COMPRISING 1,2,3-TRIAZOLES | MERCK PATENT GMBH (DE) | 2013-07-04 | — | — | WO | disclosed |
| WO-2013087162-A1 | ORGANIC SENSITIZERS FOR UP-CONVERSION | MERCK PATENT GMBH (DE) | 2013-06-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10403833-B2 | Organic metal complexes | SOD1, ORC3, PPIA | CA2 1041/4885CA1 1275/4885CA5A 614/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.