Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 5/20 | 0.64 |
| ▸ | NFE2L2 | Q16236 | 5/20 | 0.64 |
| ▸ | CA2 | P00918 | 3/20 | 0.55 |
| ▸ | CA1 | P00915 | 2/20 | 0.55 |
| ▸ | CA5A | P35218 | 1/20 | 0.55 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.55 |
| ▸ | CA12 | O43570 | 3/20 | 0.54 |
| ▸ | CA9 | Q16790 | 3/20 | 0.54 |
| ▸ | KDR | P35968 | 2/20 | 0.53 |
| ▸ | STS | P08842 | 1/20 | 0.52 |
| ▸ | RXRA | P19793 | 2/20 | 0.50 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.50 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | KDM6B | O15054 | 1/20 | 0.48 |
| ▸ | KDM5C | P41229 | 1/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.48 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.48 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.48 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14226896 | 0.90 | KEAP1 (0.71) | KEAP1NFE2L2CA2CA1CA5A | |
| SCHEMBL31473210 | 0.87 | KDR (0.60) | KEAP1NFE2L2CA2CA1CA5A | |
| SCHEMBL15040972 | 0.82 | CA2 (0.67) | KEAP1NFE2L2CA2CA1CA5A | |
| SCHEMBL31473225 | 0.82 | KEAP1 (0.62) | KEAP1NFE2L2CA2CA1CA5A | |
| SCHEMBL22643388 | 0.80 | KEAP1 (0.64) | KEAP1NFE2L2CA2CA1CA12 | |
| SCHEMBL16307343 | 0.80 | CA2 (0.71) | KEAP1NFE2L2CA2CA1CA5A | |
| SCHEMBL31473217 | 0.80 | CA2 (0.71) | KEAP1NFE2L2CA2CA1CA5A | |
| SCHEMBL23557659 | 0.79 | HSD17B1 (0.76) | KEAP1NFE2L2CA2CA1CA5A | |
| SCHEMBL18031108 | 0.79 | HSD17B1 (0.76) | KEAP1NFE2L2CA2CA1CA5A | |
| SCHEMBL14226893 | 0.77 | KEAP1 (0.60) | KEAP1NFE2L2CA2CA1CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119591559-A | Method for constructing iminothiazole derivative by promoting denitrification of 1,2, 3-triazole by alkali | 昆明理工大学 | 2025-03-11 | — | — | CN | disclosed |