Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.46 |
| ▸ | TDO2 | P48775 | 1/20 | 0.46 |
| ▸ | FABP3 | P05413 | 1/20 | 0.44 |
| ▸ | FABP4 | P15090 | 1/20 | 0.44 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 5/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MYC | P01106 | 1/20 | 0.42 |
| ▸ | HSPA1A | P0DMV8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL181735 | 0.82 | MAOA (0.45) | IDO1TDO2L3MBTL1MAOAMAOB | |
| SCHEMBL181817 | 0.80 | ALDH1A1 (0.49) | L3MBTL1MAOAMAOBPOLBMEN1 | |
| SCHEMBL17125413 | 0.80 | BCL2 (0.51) | IDO1FABP3FABP4FABP5L3MBTL1 | |
| SCHEMBL182136 | 0.79 | KEAP1 (0.51) | L3MBTL1MAOAMAOBPOLBMEN1 | |
| SCHEMBL2710273 | 0.78 | KMO (0.49) | L3MBTL1MAOAMAOBPOLBMEN1 | |
| SCHEMBL27824806 | 0.77 | KMO (0.59) | L3MBTL1MAOAMAOBPOLBMEN1 | |
| SCHEMBL3927376 | 0.77 | GRM5 (0.61) | L3MBTL1MAOAMAOBPOLBMEN1 | |
| SCHEMBL30794485 | 0.77 | GRM5 (0.61) | L3MBTL1MAOAMAOBPOLBMEN1 | |
| SCHEMBL182162 | 0.76 | KMO (0.53) | POLBALDH1A1KDM4EGRM5STIM1 | |
| SCHEMBL181938 | 0.76 | MEN1 (0.49) | L3MBTL1MAOAMAOBPOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2363129-A1 | Pyrazole or triazole compounds and their use for the manufacture of a medicament for treating somatic mutation-related diseases | PTC Therapeutics, Inc. (US) | 2011-09-07 | — | — | EP | disclosed |