Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.34 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.34 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.31 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.31 |
| ▸ | CLK1 | P49759 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16357 | 0.83 | KDM4E (0.32) | CSNK1DCSNK1ECLK1DYRK1A | |
| SCHEMBL4750437 | 0.79 | CLK1 (0.47) | CSNK1DCSNK1ECLK1DYRK1A | |
| SCHEMBL4750547 | 0.79 | CLK1 (0.47) | CSNK1DCSNK1ECLK1DYRK1A | |
| SCHEMBL23454 | 0.75 | MAPK10 (0.43) | CLK1DYRK1A | |
| SCHEMBL2042187 | 0.73 | — | — | |
| SCHEMBL24395 | 0.72 | CLK1 (0.46) | CLK1DYRK1A | |
| SCHEMBL17511895 | 0.71 | IMPDH2 (0.40) | CSNK1DCLK1DYRK1A | |
| SCHEMBL2910 | 0.70 | CYP1A2 (0.44) | — | |
| SCHEMBL156192 | 0.70 | MAP4K4 (0.31) | MAP4K4MINK1TNIKCSNK1DCSNK1E | |
| SCHEMBL449631 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Appears in 2802 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024106781-A1 | LIPID COMPOUND AND COMPOSITION FOR DELIVERY OF ACTIVE SUBSTANCE | 한국생명공학연구원 | 2024-05-23 | — | — | WO | claimed |
| US-11964973-B2 | Substituted bicyclic compounds useful as T cell activators | BRISTOL-MYERS SQUIBB COMPANY (US) | 2024-04-23 | — | — | US | claimed |
| CN-117088869-A | 3CL protease inhibitor and preparation method and application thereof | 上海翊石医药科技有限公司 | 2023-11-21 | — | — | CN | claimed |
| CN-117083271-A | Substituted thiadiazolyl derivatives as DNA polymerase theta inhibitors | 伊迪亚生物科学有限公司 | 2023-11-17 | — | — | CN | claimed |
| EP-3810116-B1 | NOVEL SUBSTITUTED [1.1.1] BICYCLO COMPOUNDS AS INDOLEAMINE 2,3-DIOXYGENASE INHIBITORS | MERCK SHARP & DOHME LLC (US) | 2023-11-15 | — | — | EP | claimed |
| EP-3976608-B1 | THIADIAZOLYL DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS | IDEAYA BIOSCIENCES INC (US) | 2023-11-08 | — | — | EP | claimed |
| EP-4255573-A1 | SUBSTITUTED THIADIAZOLYL DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS | Ideaya Biosciences, Inc. (US) | 2023-10-11 | — | — | EP | claimed |
| CN-111490175-B | Organic light emitting device | 三星显示有限公司 | 2023-06-06 | — | — | CN | claimed |
| CN-111211247-B | Organic light emitting device | 三星显示有限公司 | 2023-04-18 | — | — | CN | claimed |
| US-20230078112-A1 | THIADIAZOLYL DERIVATIVES | IDEAYA BIOSCIENCES, INC. | 2023-03-16 | — | — | US | claimed |
| US-5434260-A | Treating transplantation rejection in mammals | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-07-18 | — | — | US | claimed |
| WO-1995013267-A1 | PYRIMIDINE-THIOALKYL AND ALKYLETHER COMPOUNDS | THE UPJOHN COMPANY (US) | 1995-05-18 | — | — | WO | claimed |
| US-5385908-A | Hindered esters of rapamycin | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-01-31 | — | — | US | claimed |
| US-5385909-A | Heterocyclic esters of rapamycin | AMERICAN HOME PRODUCTS CORPORATION (US) | 1995-01-31 | — | — | US | claimed |
| EP-0289430-B1 | SWEETENERS DERIVED FROM GUANIDINOACETIC AND ETHANAMIDINOACETIC ACIDS, THEIR USES AND COMPOSITIONS CONTAINING THESE SWEETENERS | UNIVERSITE CLAUDE BERNARD - LYON 1 (FR) | 1992-04-08 | — | — | EP | claimed |
| US-4822790-A | ANTIMICROBIOCIDES OR BETA-LACTAMASE INHIBITORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1989-04-18 | — | — | US | claimed |
| US-4536208-A | Certain naphthyridine diether compounds and their herbicidal use | THE DOW CHEMICAL COMPANY (US) | 1985-08-20 | — | — | US | claimed |
| US-4533381-A | Naphthyridinyloxy(or thio)phenoxy propanoic acids, derivatives thereof and methods of herbicidal use | THE DOW CHEMICAL COMPANY (US) | 1985-08-06 | — | — | US | claimed |
| US-4472193-A | Naphthyridinyloxy(or thio)phenoxy propanoic acids, derivatives thereof and methods of herbicidal use | THE DOW CHEMICAL COMPANY (US) | 1984-09-18 | — | — | US | claimed |
| US-4416817-A | BACTERICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-11-22 | — | — | US | claimed |