SCHEMBL2910

SCHEMBL2910

[c]1ccc2ccccc2n1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 1/20 0.44
ALDH1A1 P00352 3/20 0.42
MAPT P10636 3/20 0.41
HPGD P15428 2/20 0.40
GLA P06280 1/20 0.40
ACHE P22303 1/20 0.40
NCF1 P14598 3/20 0.39
NOS2 P35228 1/20 0.39
BACE1 P56817 1/20 0.39
CA12 O43570 1/20 0.39
CA9 Q16790 1/20 0.39
NQO2 P16083 1/20 0.39
KDM4E B2RXH2 3/20 0.36
NPC1 O15118 1/20 0.36
LMNA P02545 1/20 0.36
PKM P14618 1/20 0.36
RAB9A P51151 1/20 0.36
HDAC8 Q9BY41 1/20 0.35
GAA P10253 1/20 0.35
HSD17B10 Q99714 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9876593 0.88 CYP1A2 (0.41) CYP1A2ALDH1A1MAPTHPGDGLA
SCHEMBL7374426 0.83 CYP1A2 (0.33) CYP1A2ALDH1A1
SCHEMBL524746 0.79 ALDH1A1 (0.46) CYP1A2ALDH1A1MAPTHPGDGLA
SCHEMBL2139252 0.78 ALDH1A1 (0.44) CYP1A2ALDH1A1MAPTHPGDGLA
SCHEMBL20659316 0.76 MAPT (0.54) CYP1A2ALDH1A1MAPTHPGDGLA
SCHEMBL449631 0.73
SCHEMBL524536 0.72 CYP3A4 (0.52) ALDH1A1MAPTKDM4ENPC1LMNA
SCHEMBL196535 0.71
SCHEMBL2671574 0.70 NPC1 (0.47) CYP1A2ALDH1A1MAPTKDM4ENPC1
SCHEMBL16316 0.70 MAP4K4 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 347469 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6432995-B1 None US claimed
JP-5155847-A None JP claimed
CN-115947646-B Method for hydroxylation of aryl or heteroaryl halides by photocatalysis 浙江工业大学 2024-07-23 CN claimed
US-12043634-B2 Metal complexes, methods of making the same, and uses thereof THE UNIVERSITY OF MANITOBA (CA) 2024-07-23 US claimed
US-20240239824-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-18 US claimed
US-20240244858-A1 ORGANOMETALLIC COMPOUND, ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME, AND ELECTRONIC APPARATUS INCLUDING THE ORGANIC LIGHT-EMITTING DEVICE SAMSUNG DISPLAY CO., LTD. (KR) 2024-07-18 US claimed
WO-2024150132-A1 LIGAND-DRUG CONJUGATES SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) 2024-07-18 WO claimed
WO-2023058644-A9 COMPOUND, ORGANIC EL ELEMENT, DISPLAY DEVICE AND LIGHTING DEVICE 東レ株式会社 2024-07-18 WO claimed
EP-3381983-B1 SQUARYLIUM COMPOUNDS AND INFRARED CUT FILMS, INFRARED CUT FILTERS AND ELECTRONIC DEVICES INCLUDING THE SAME SAMSUNG ELECTRONICS CO LTD (KR) 2024-07-17 EP claimed
CN-118355015-A N- (5-substituted- [ (1, 3, 4-thiadiazole) or (thiazolyl) ]) (substituted) carboxamide compounds for inhibiting human polymerase θ and uses thereof 修复治疗公司 2024-07-16 CN claimed
US-3948917-A TRANQUILIZERS, ANTICONVULSANTS, DECONTRACTURANTS, HYPNOSIS RHONE-POULENC S.A. (FR) 1976-04-06 US claimed
US-3947410-A OPTICAL BRIGHTENERS CIBA-GEIGY CORPORATION (US) 1976-03-30 US claimed
US-3943125-A Substituted tetraamino heterocyclic compounds, useful in the preparation of substituted polybenzimidazoles and poly-imidazopyrrolones HORIZONS INCORPORATED, A DIVISION OF HORIZONS RESEARCH INCORPORATED (US) 1976-03-09 US claimed
US-3935198-A BY HEATING THE PENICILLIN SULFOXIDE YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) 1976-01-27 US claimed
US-3933786-A Heterocyclic-azo-phenyl compounds containing a styrl group CIBA-GEIGY AG (CH) 1976-01-20 US claimed
US-3933811-A N-aminomethyl-2-amino(and 2-amino-methyl)-2-(2-quinolyl)-thioacetamides SMITHKLINE CORPORATION (US) 1976-01-20 US claimed
US-3933819-A SURFACTANTS PENNWALT CORPORATION (US) 1976-01-20 US claimed
US-3932645-A CORONARY VASODILATORS, HYPOTENSIVE AGENTS FARBENFABRIKEN BAYER AG (DT) 1976-01-13 US claimed
US-3932301-A NYLON, POLYESTERS STERLING DRUG INC. (US) 1976-01-13 US claimed
US-3931162-A N-Aminomethyl heterocyclic thioacetamides SMITHKLINE CORPORATION (US) 1976-01-06 US claimed