Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.56 |
| ▸ | FFAR1 | O14842 | 9/20 | 0.54 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.49 |
| ▸ | TOP1 | P11387 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.46 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20252664 | 0.85 | MAOB (0.57) | MAOBFFAR1TOP1PPARDKDM4E | |
| SCHEMBL27771711 | 0.84 | MAOB (0.58) | MAOBABCB1HTR1ADRD2KDM4E | |
| SCHEMBL15365 | 0.82 | MAOB (0.58) | MAOBFFAR1MAPT | |
| SCHEMBL31166954 | 0.80 | ALOX5 (0.58) | MAOBTOP1MAOAMAPT | |
| SCHEMBL2501392 | 0.80 | FFAR1 (0.75) | FFAR1 | |
| SCHEMBL2496055 | 0.80 | FFAR1 (0.75) | FFAR1 | |
| SCHEMBL27882779 | 0.79 | MAOB (0.58) | MAOBFFAR1ABCB1HTR1ADRD2 | |
| SCHEMBL20244889 | 0.78 | MAPT (0.53) | MAOBKDM4EMAPT | |
| SCHEMBL23520334 | 0.77 | MAPT (0.49) | MAOBKDM4EMAPT | |
| SCHEMBL18044481 | 0.76 | MAOB (0.58) | MAOBFFAR1PPARDMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9382188-B2 | Aromatic ring compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2016-07-05 | — | — | US | disclosed |
| EP-2816023-A1 | AROMATIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2014-12-24 | — | — | EP | disclosed |