Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 5/20 | 0.58 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.53 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.50 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.48 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31166954 | 0.88 | ALOX5 (0.58) | MAOBALOX5MAPTSMN1; SMN2GAA | |
| SCHEMBL27771711 | 0.87 | MAOB (0.58) | MAOBALDH1A1MAPTALOX12SMN1; SMN2 | |
| SCHEMBL18044481 | 0.87 | MAOB (0.58) | MAOBALOX5PDGFRBPDGFRAALDH1A1 | |
| SCHEMBL2090976 | 0.83 | MAOB (0.62) | MAOBALOX5PDGFRBPDGFRAALDH1A1 | |
| SCHEMBL18623122 | 0.83 | MAOB (0.62) | MAOBALOX5PDGFRBPDGFRAALDH1A1 | |
| SCHEMBL20252664 | 0.83 | MAOB (0.57) | MAOBALOX5ALDH1A1MAPTALOX12 | |
| SCHEMBL8280802 | 0.82 | MAOB (0.60) | MAOBALOX5PDGFRBPDGFRAALDH1A1 | |
| SCHEMBL16319277 | 0.82 | MAOB (0.56) | MAOBMAPTFFAR1 | |
| SCHEMBL15817 | 0.81 | ALOX5 (0.61) | MAOBALOX5MAPTSMN1; SMN2GAA | |
| SCHEMBL1550410 | 0.81 | MAOB (0.58) | MAOBALOX5ALDH1A1MAPTALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2609065-B1 | PROCESSES FOR PRODUCING 1-BROMO-2 (CYCLOPROPYL METHOXY)-5 FLUORO-4- METHOXYBENZENE | ALBEMARLE CORP (US) | 2015-07-08 | — | — | EP | claimed |
| EP-2609065-A1 | PROCESSES FOR PRODUCING 1-BROMO-2 (CYCLOPROPYL METHOXY)-5 FLUORO-4- METHOXYBENZENE | Albemarle Corporation (US) | 2013-07-03 | — | — | EP | claimed |
| US-20130109887-A1 | PROCESSES FOR PRODUCING 1-BROMO-2- (CYCLOPROPYL METHOXY)-5-FLUORO-4-METHOXYBENZENE | ALBERMARLE CORPORATION (US) | 2013-05-02 | — | — | US | claimed |
| WO-2012027134-A1 | PROCESSES FOR PRODUCING 1-BROMO-2 (CYCLOPROPYL METHOXY)-5 FLUORO-4- METHOXYBENZENE | ALBEMARLE CORPORATION (US) | 2012-03-01 | — | — | WO | claimed |
| EP-2609065-B1 | PROCESSES FOR PRODUCING 1-BROMO-2 (CYCLOPROPYL METHOXY)-5 FLUORO-4- METHOXYBENZENE | ALBEMARLE CORP (US) | 2015-07-08 | — | — | EP | disclosed |
| EP-2609065-B1 | PROCESSES FOR PRODUCING 1-BROMO-2 (CYCLOPROPYL METHOXY)-5 FLUORO-4- METHOXYBENZENE | ALBEMARLE CORP (US) | 2015-07-08 | — | — | EP | disclosed |
| EP-2609065-A1 | PROCESSES FOR PRODUCING 1-BROMO-2 (CYCLOPROPYL METHOXY)-5 FLUORO-4- METHOXYBENZENE | Albemarle Corporation (US) | 2013-07-03 | — | — | EP | disclosed |
| US-20130109887-A1 | PROCESSES FOR PRODUCING 1-BROMO-2- (CYCLOPROPYL METHOXY)-5-FLUORO-4-METHOXYBENZENE | ALBERMARLE CORPORATION (US) | 2013-05-02 | — | — | US | disclosed |
| US-20130109887-A1 | PROCESSES FOR PRODUCING 1-BROMO-2- (CYCLOPROPYL METHOXY)-5-FLUORO-4-METHOXYBENZENE | ALBERMARLE CORPORATION (US) | 2013-05-02 | — | — | US | disclosed |
| US-20130109887-A1 | PROCESSES FOR PRODUCING 1-BROMO-2- (CYCLOPROPYL METHOXY)-5-FLUORO-4-METHOXYBENZENE | ALBERMARLE CORPORATION (US) | 2013-05-02 | — | — | US | disclosed |
| WO-2012027134-A1 | PROCESSES FOR PRODUCING 1-BROMO-2 (CYCLOPROPYL METHOXY)-5 FLUORO-4- METHOXYBENZENE | ALBEMARLE CORPORATION (US) | 2012-03-01 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130109887-A1 | PROCESSES FOR PRODUCING 1-BROMO-2- (CYCLOPROPYL METHOXY)-5-FLUORO-4-METHOXYBENZENE | CYP4B1, CYP4X1, CYP1B1 | MAOB 30/4885ALOX5 893/4885PDGFRB 677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.