SCHEMBL16319356

SCHEMBL16319356

CNC(=O)C(=NOC)C(C)=CCOc1ccn(-c2ccc(F)cc2F)n1

nearest known ligand 0.33

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
GPR35 Q9HC97 1/20 0.33
CNR1 P21554 2/20 0.31
CNR2 P34972 2/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
KDM4E B2RXH2 1/20 0.31
ALDH1A1 P00352 1/20 0.31
MAPT P10636 1/20 0.31
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16319355 1.00 GPR35 (0.33) GPR35CNR1CNR2L3MBTL1KDM4E
SCHEMBL16319353 1.00 GPR35 (0.33) GPR35CNR1CNR2L3MBTL1KDM4E
SCHEMBL16318970 0.92 ATP4A (0.33)
SCHEMBL16318973 0.92 ATP4A (0.33)
SCHEMBL16318972 0.92 ATP4A (0.33)
SCHEMBL16319140 0.91 NUDT1 (0.33)
SCHEMBL16319142 0.91 NUDT1 (0.33)
SCHEMBL29367593 0.91 NUDT1 (0.33)
SCHEMBL16319139 0.91 NUDT1 (0.33)
SCHEMBL16318776 0.85 KCNH2 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 24 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190098899-A1 FUNGICIDAL MIXTURES III COMPRISING STROBILURIN-TYPE FUNGICIDES BASF SE (DE) 2019-04-04 US claimed
US-20180235221-A1 FUNGICIDAL MIXTURES COMPRISING STROBILURIN-TYPE FUNGICIDES BASF SE (DE) 2018-08-23 US claimed
EP-3267797-A1 FUNGICIDAL MIXTURES COMPRISING STROBILURIN-TYPE FUNGICIDES BASF SE (DE) 2018-01-17 EP claimed
EP-3010344-B1 FUNGICIDAL MIXTURES I COMPRISING STROBILURIN-TYPE FUNGICIDES BASF SE (DE) 2017-11-15 EP claimed
US-9763448-B2 Fungicidal mixtures I comprising strobilurin-type fungicides BASF SE (DE) 2017-09-19 US claimed
WO-2016142224-A1 FUNGICIDAL MIXTURES COMPRISING STROBILURIN-TYPE FUNGICIDES BASF SE (DE) 2016-09-15 WO claimed
EP-2815650-B1 Fungicidal mixtures II comprising strobilurin-type fungicides BASF SE (DE) 2016-08-17 EP claimed
US-20160135459-A1 FUNGICIDAL MIXTURES I COMPRISING STROBILURIN-TYPE FUNGICIDES BASF Agro B.V. (NL) 2016-05-19 US claimed
EP-2835052-A1 Fungicidal mixtures comprising pyrimidine fungicides BASF SE (DE) 2015-02-11 EP claimed
EP-2815650-A1 Fungicidal mixtures II comprising strobilurin-type fungicides BASF SE (DE) 2014-12-24 EP claimed
EP-2815649-A1 Fungicidal mixtures II comprising strobilurin-type fungicides BASF SE (DE) 2014-12-24 EP claimed
US-20190098899-A1 FUNGICIDAL MIXTURES III COMPRISING STROBILURIN-TYPE FUNGICIDES BASF SE (DE) 2019-04-04 US disclosed
US-20180235221-A1 FUNGICIDAL MIXTURES COMPRISING STROBILURIN-TYPE FUNGICIDES BASF SE (DE) 2018-08-23 US disclosed
EP-3010344-B1 FUNGICIDAL MIXTURES I COMPRISING STROBILURIN-TYPE FUNGICIDES BASF SE (DE) 2017-11-15 EP disclosed
US-9763448-B2 Fungicidal mixtures I comprising strobilurin-type fungicides BASF SE (DE) 2017-09-19 US disclosed
WO-2015036059-A1 FUNGICIDAL PYRIMIDINE COMPOUNDS BASF SE (DE) 2015-03-19 WO disclosed
WO-2015036058-A1 FUNGICIDAL PYRIMIDINE COMPOUNDS BASF SE (DE) 2015-03-19 WO disclosed
EP-2835052-A1 Fungicidal mixtures comprising pyrimidine fungicides BASF SE (DE) 2015-02-11 EP disclosed
EP-2815650-A1 Fungicidal mixtures II comprising strobilurin-type fungicides BASF SE (DE) 2014-12-24 EP disclosed
EP-2815649-A1 Fungicidal mixtures II comprising strobilurin-type fungicides BASF SE (DE) 2014-12-24 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180235221-A1 FUNGICIDAL MIXTURES COMPRISING STROBILURIN-TYPE FUNGICIDES DDT, STS, SNX1 GPR35 4584/4885CNR1 4585/4885CNR2 4710/4885
US-20160135459-A1 FUNGICIDAL MIXTURES I COMPRISING STROBILURIN-TYPE FUNGICIDES STS, SNX1, SFXN1 GPR35 4695/4885CNR1 4685/4885CNR2 4831/4885
US-20190098899-A1 FUNGICIDAL MIXTURES III COMPRISING STROBILURIN-TYPE FUNGICIDES DDT, SNX3, SFXN3 GPR35 4651/4885CNR1 4705/4885CNR2 4818/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.