Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.38 |
| ▸ | IDH2 | P48735 | 1/20 | 0.36 |
| ▸ | SGK1 | O00141 | 2/20 | 0.36 |
| ▸ | USP8 | P40818 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | HPGDS | O60760 | 1/20 | 0.36 |
| ▸ | CTSS | P25774 | 1/20 | 0.35 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16319017 | 0.81 | FFAR1 (0.42) | FFAR1IDH2SGK1NPC1RAB9A | |
| SCHEMBL16318882 | 0.76 | FFAR1 (0.43) | FFAR1SGK1NPC1RAB9AKDM4E | |
| SCHEMBL16319342 | 0.75 | FFAR1 (0.45) | FFAR1IDH2SGK1NPC1RAB9A | |
| SCHEMBL16319023 | 0.75 | FFAR1 (0.45) | FFAR1GRM2IDH2SGK1NPC1 | |
| SCHEMBL16318846 | 0.72 | FFAR1 (0.43) | FFAR1GRM2IDH2SGK1KDM4E | |
| SCHEMBL16319368 | 0.70 | FFAR1 (0.39) | FFAR1IDH2NPC1RAB9AKDM4E | |
| SCHEMBL16318461 | 0.69 | MAP3K7 (0.39) | CTSSCTSKPOLBMEN1KMT2A | |
| SCHEMBL16319382 | 0.68 | CASP3 (0.42) | FFAR1NPC1RAB9AKDM4EALDH1A1 | |
| SCHEMBL16319385 | 0.67 | FFAR1 (0.42) | FFAR1IDH2NPC1RAB9ACYP11B1 | |
| SCHEMBL17621384 | 0.66 | OPRL1 (0.36) | CYP11B1CYP11B2CTSSCTSKSQOR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9181186-B2 | Aromatic ring compound | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-11-10 | — | — | US | disclosed |
| US-20150045378-A1 | AROMATIC RING COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2015-02-12 | — | — | US | disclosed |
| EP-2816032-A1 | AROMATIC RING COMPOUND | Takeda Pharmaceutical Company Limited (JP) | 2014-12-24 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150045378-A1 | AROMATIC RING COMPOUND | GPR119, GPR27, GPR4 | FFAR1 31/4885GRM2 765/4885IDH2 4057/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.