Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA2 | P47869 | 4/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | PDE2A | O00408 | 2/20 | 0.37 |
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 4/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | GABRP | O00591 | 1/20 | 0.36 |
| ▸ | GABRD | O14764 | 1/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.36 |
| ▸ | GABRE | P78334 | 1/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1768628 | 0.77 | PDE2A (0.40) | GABRA2GABRB2ALDH1A1SMN1; SMN2PDE2A | |
| SCHEMBL16320344 | 0.76 | RAPGEF4 (0.42) | ALDH1A1RAPGEF4KMT2ALMNAHTT | |
| SCHEMBL241686 | 0.72 | ALDH1A1 (0.42) | GABRA2GABRB2ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL16340964 | 0.72 | MAPT (0.46) | ALDH1A1RAPGEF4LMNA | |
| SCHEMBL9725591 | 0.72 | PDE2A (0.40) | GABRA2GABRB2ALDH1A1SMN1; SMN2KDM4E | |
| Hydrochloric Acid SCHEMBL5745583 | 0.71 | ALDH1A1 (0.41) | GABRA2GABRB2ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL18593305 | 0.71 | RAPGEF4 (0.46) | GABRA2GABRB2ALDH1A1SMN1; SMN2PDE2A | |
| SCHEMBL13550111 | 0.70 | RAPGEF4 (0.44) | GABRA2GABRB2ALDH1A1PDE2ARAPGEF4 | |
| SCHEMBL10280738 | 0.69 | GABRA2 (0.38) | GABRA2GABRB2ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL7801589 | 0.69 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2KDM4EMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9441059-B2 | Metathesis catalysts and methods thereof | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2016-09-13 | — | — | US | disclosed |
| US-20140378637-A1 | METATHESIS CATALYSTS AND METHODS THEREOF | NATIONAL SCIENCE FOUNDATION | 2014-12-25 | — | — | US | disclosed |