Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | RAPGEF4 | Q8WZA2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | TXNRD1 | Q16881 | 1/20 | 0.35 |
| ▸ | TXNRD3 | Q86VQ6 | 1/20 | 0.35 |
| ▸ | TXNRD2 | Q9NNW7 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1768628 | 0.77 | PDE2A (0.40) | PDE2ARAPGEF4SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL241686 | 0.77 | ALDH1A1 (0.42) | PDE2ARAPGEF4SMN1; SMN2ALDH1A1CYP3A4 | |
| Hydrochloric Acid SCHEMBL5745583 | 0.76 | ALDH1A1 (0.41) | PDE2ARAPGEF4SMN1; SMN2ALDH1A1CYP3A4 | |
| SCHEMBL10695243 | 0.73 | PDE2A (0.39) | PDE2ASMN1; SMN2ALDH1A1CYP3A4HPGD | |
| SCHEMBL16320650 | 0.72 | GABRA2 (0.38) | PDE2ARAPGEF4SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL28714280 | 0.72 | PDE2A (0.37) | PDE2ARAPGEF4ALDH1A1CYP3A4HPGD | |
| SCHEMBL12864135 | 0.72 | GABRB3 (0.36) | PDE2ARAPGEF4SMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL981089 | 0.72 | ALDH1A1 (0.46) | PDE2ASMN1; SMN2ALDH1A1CYP3A4HPGD | |
| SCHEMBL7710562 | 0.71 | ALDH1A1 (0.41) | PDE2ASMN1; SMN2ALDH1A1GPR35MAPT | |
| SCHEMBL7713982 | 0.71 | PDE2A (0.40) | PDE2ASMN1; SMN2ALDH1A1GPR35MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5095032-A | PARASITICIDAL NEW SUBSTITUTED THIENOPYRANONES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-10 | — | — | US | disclosed |
| US-4804655-A | Pesticidal cyclic malonylphosphonic diamides | BAYER AKTIENGESELLSCHAFT (DE) | 1989-02-14 | — | — | US | disclosed |
| US-4771048-A | VETERINARY MEDICINE | BAYER AKTIENGESELLSCHAFT (DE) | 1988-09-13 | — | — | US | disclosed |
| US-4766144-A | 3-carbamoyl-4-hydroxy-coumarins for combating parasitic heiminths | BAYER AKTIENGESELLSCHAFT (DE) | 1988-08-23 | — | — | US | disclosed |