Known targets — ChEMBL curated mechanism
GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQ
The experimentally established mechanism targets of Water. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 4/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 4/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 4/20 | 0.45 |
| ▸ | TSHR | P16473 | 4/20 | 0.45 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.45 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.43 |
| ▸ | CPT2 | P23786 | 1/20 | 0.40 |
| ▸ | CPT1A | P50416 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | GALR3 | O60755 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL675895 | 0.97 | LMNA (0.46) | LMNACHRM2CHRM4CHRM1TSHR | |
| Bromide SCHEMBL3917464 | 0.95 | LMNA (0.45) | LMNACHRM2CHRM4CHRM1TSHR | |
| Hydrochloric Acid SCHEMBL4199984 | 0.95 | LMNA (0.48) | LMNACHRM2CHRM4CHRM1TSHR | |
| Hydrochloric Acid SCHEMBL7631402 | 0.95 | LMNA (0.45) | LMNACHRM2CHRM4CHRM1TSHR | |
| SCHEMBL52510 | 0.74 | MAPT (0.46) | LMNACHRM2CHRM4CHRM1TSHR | |
| SCHEMBL10529054 | 0.73 | MAPT (0.41) | LMNACHRM2CHRM4CHRM1TSHR | |
| SCHEMBL5582502 | 0.72 | MAPT (0.44) | LMNACHRM2CHRM4CHRM1TSHR | |
| SCHEMBL27896693 | 0.72 | LMNA (0.52) | LMNACHRM2CHRM4CHRM1TSHR | |
| Hydrochloric Acid SCHEMBL9486928 | 0.72 | MAPT (0.50) | LMNACHRM2CHRM4CHRM1TSHR | |
| Iodide SCHEMBL6748621 | 0.72 | MAPT (0.44) | LMNACHRM2CHRM4CHRM1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9057959-B2 | Developer for photosensitive resist material and patterning process | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2015-06-16 | — | — | US | disclosed |
| US-20140377706-A1 | DEVELOPER FOR PHOTOSENSITIVE RESIST MATERIAL AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2014-12-25 | — | — | US | disclosed |