Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.55 |
| ▸ | TSHR | P16473 | 3/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | PARP1 | P09874 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | BLM | P54132 | 1/20 | 0.55 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 8/20 | 0.52 |
| ▸ | CES2 | O00748 | 7/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | DAO | P14920 | 1/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | CA12 | O43570 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL272138 | 0.83 | TDP1 (0.55) | TDP1TSHRCYP3A4MAPTHSD17B10 | |
| SCHEMBL18687120 | 0.80 | TDP1 (0.57) | TDP1TSHRCYP3A4MAPTHSD17B10 | |
| SCHEMBL30863826 | 0.78 | TDP1 (0.55) | TDP1TSHRCYP3A4MAPTHSD17B10 | |
| SCHEMBL21879778 | 0.76 | ALDH1A1 (0.59) | TDP1MAPTCES1CES2ALDH1A1 | |
| SCHEMBL4019209 | 0.75 | CES1 (0.48) | TDP1TSHRCYP3A4MAPTHSD17B10 | |
| SCHEMBL22204644 | 0.75 | CES1 (0.48) | TDP1TSHRCYP3A4MAPTHSD17B10 | |
| SCHEMBL274249 | 0.75 | CES1 (0.48) | TDP1TSHRCYP3A4MAPTHSD17B10 | |
| Benzamide SCHEMBL28132124 | 0.72 | PARP1 (0.89) | TDP1TSHRCYP3A4MAPTHSD17B10 | |
| Benzamide SCHEMBL27340650 | 0.72 | PARP1 (0.89) | TDP1TSHRCYP3A4MAPTHSD17B10 | |
| Benzamide SCHEMBL2061911 | 0.72 | PARP1 (0.89) | TDP1TSHRCYP3A4MAPTHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 86 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3119377-B1 | PHOTOPOLYMERISABLE AND DUAL HARDENING DENTAL MATERIAL BASED ON THIOUREA DERIVATIVES AND BISACYLDIALKYLGERMANIUM-COMPOUNDS | IVOCLAR VIVADENT AG (LI) | 2021-12-29 | — | — | EP | claimed |
| CN-106132380-B | Photopolymerizable dual-cure dental materials based on thiourea derivatives | 义获嘉伟瓦登特公司 | 2020-02-11 | — | — | CN | claimed |
| EP-2921156-B1 | Monomer mixture for the preparation of dental materials | IVOCLAR VIVADENT AG (LI) | 2019-10-02 | — | — | EP | claimed |
| US-10195121-B2 | Photopolymerizable and dual-curing dental materials based on thiourea derivatives | IVOCLAR VIVADENT AG (LI) | 2019-02-05 | — | — | US | claimed |
| US-10130562-B2 | Monomer mixture for the preparation of dental materials | IVOCLAR VIVADENT AG (LI) | 2018-11-20 | — | — | US | claimed |
| US-20170143592-A1 | MONOMER MIXTURE FOR THE PREPARATION OF DENTAL MATERIALS | IVOCLAR VIVADENT AG (LI) | 2017-05-25 | — | — | US | claimed |
| US-20170128328-A1 | Photopolymerizable and dual-curing dental materials based on thiourea derivatives | IVOCLAR VIVADENT AG (LI) | 2017-05-11 | — | — | US | claimed |
| EP-2921154-B1 | Photopolymerisable and dual hardening dental material based on thiourea derivatives and bisacyldialkylgermanium-compounds | IVOCLAR VIVADENT AG (LI) | 2017-03-08 | — | — | EP | claimed |
| EP-2921156-A1 | Monomer mixture for the preparation of dental materials | Ivoclar Vivadent AG (LI) | 2015-09-23 | — | — | EP | claimed |
| EP-2921154-A1 | Photopolymerisable and dual hardening dental material based on thiourea derivatives and bisacyldialkylgermanium-compounds | Ivoclar Vivadent AG (LI) | 2015-09-23 | — | — | EP | claimed |
| EP-4717249-A1 | DENTAL COMPOSITION | Shofu Inc. (JP) | 2026-04-01 | — | — | EP | disclosed |
| US-20260083642-A1 | DENTAL COMPOSITION | SHOFU INC (JP) | 2026-03-26 | — | — | US | disclosed |
| US-20260083644-A1 | METHOD FOR PRODUCING DENTAL POLYMERIZABLE COMPOSITION OR DENTAL POLYMERIZABLE COMPOSITION INTERMEDIATE | SHOFU INC (JP) | 2026-03-26 | — | — | US | disclosed |
| US-20260060900-A1 | DENTAL COMPOSITE RESIN KIT | SHOFU INC. (JP) | 2026-03-05 | — | — | US | disclosed |
| US-20250381101-A1 | HIGHLY FLOWABLE DENTAL CURABLE COMPOSITION | SHOFU INC. (JP) | 2025-12-18 | — | — | US | disclosed |
| US-20100068679-A1 | Dental materials with a high flexural modulus | IVOCLAR VIVADENT AG (LI) | 2010-03-18 | — | — | US | disclosed |
| EP-2163235-A1 | Dental materials with high bending module | Ivoclar Vivadent AG (LI) | 2010-03-17 | — | — | EP | disclosed |
| EP-1974712-A1 | Dental material based on radically polymerisable N,O-functionalised acrylic acid hydroxamides | Ivoclar Vivadent AG (LI) | 2008-10-01 | — | — | EP | disclosed |
| US-20080234405-A1 | very quickly cured; particularly suitable for dental purposes | IVOCLAR VIVADENT AG (LI) | 2008-09-25 | — | — | US | disclosed |
| US-20080076847-A1 | Polymerizable compositions with acylgermanes as initiatiors | IVOCLAR VIVADENT AG (LI) | 2008-03-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260060900-A1 | DENTAL COMPOSITE RESIN KIT | BOLA2; BOLA2B, LBR, COL2A1 | TDP1 1382/4885TSHR 3276/4885CYP3A4 4813/4885 |
| US-20260083644-A1 | METHOD FOR PRODUCING DENTAL POLYMERIZABLE COMPOSITION OR DENTAL POLYMERIZABLE COMPOSITION INTERMEDIATE | ARCN1, LBR, POLL | TDP1 772/4885TSHR 3634/4885CYP3A4 2914/4885 |
| US-20250381101-A1 | HIGHLY FLOWABLE DENTAL CURABLE COMPOSITION | RCC1, H1-0, H1-3 | TDP1 2386/4885TSHR 2062/4885CYP3A4 3140/4885 |
| US-20080076847-A1 | Polymerizable compositions with acylgermanes as initiatiors | NR1I3, NR4A1, NR1I2 | TDP1 4575/4885TSHR 807/4885CYP3A4 151/4885 |
| US-20080234405-A1 | very quickly cured; particularly suitable for dental purposes | HRH4, HRH2, HRH3 | TDP1 4522/4885TSHR 3656/4885CYP3A4 324/4885 |
| US-20260083642-A1 | DENTAL COMPOSITION | TAS2R42, COL2A1, TAS2R1 | TDP1 2239/4885TSHR 1588/4885CYP3A4 4710/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.