SCHEMBL163293

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL163539	0.80	KMO (0.50)	GABRPGABRDGABRA1GABRB1GABRG2
	SCHEMBL30521607	0.78	ADORA3 (0.42)	MKNK1MKNK2PARP1P2RX7ROCK1
	SCHEMBL3906535	0.78	ADORA3 (0.42)	MKNK1MKNK2PARP1P2RX7ROCK1
	SCHEMBL163294	0.78	KDM4E (0.37)	MKNK1MKNK2PARP1P2RX7ROCK1
	SCHEMBL669901	0.78	MKNK1 (0.42)	MKNK1MKNK2PARP1GABRPGABRD
	SCHEMBL2465653	0.77	KMT2A (0.50)	PARP1MAP4K4L3MBTL1KMT2ASIRT3
	SCHEMBL10718871	0.77	CSNK2A1 (0.36)	MKNK1MKNK2PARP1P2RX7ROCK1
	SCHEMBL2801014	0.77	PARP1 (0.35)	MKNK1MKNK2PARP1GABRPGABRD
	SCHEMBL1206986	0.77	MAP4K4 (0.40)	PARP1ROCK1KDM4BKDM5CKDM5B
	SCHEMBL162373	0.74	PLK1 (0.39)	MKNK1MKNK2P2RX7KDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.