Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA1 | P42261 | 2/20 | 0.55 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.51 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 2/20 | 0.49 |
| ▸ | CTSK | P43235 | 2/20 | 0.49 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | CHRND | Q07001 | 5/20 | 0.46 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.46 |
| ▸ | CHRNG | P07510 | 1/20 | 0.46 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16330572 | 0.93 | OPRD1 (0.59) | GRIA1OPRD1OPRM1OPRK1CTSS | |
| SCHEMBL31458711 | 0.86 | GRIA1 (0.55) | GRIA1OPRD1OPRM1OPRK1CTSS | |
| SCHEMBL22927776 | 0.85 | CTSS (0.67) | OPRD1OPRM1OPRK1CTSSCTSK | |
| SCHEMBL9724062 | 0.84 | GRIA1 (0.59) | GRIA1OPRD1OPRM1OPRK1CTSS | |
| SCHEMBL24724924 | 0.83 | GRIA1 (0.57) | GRIA1CTSSCTSKCTSL | |
| SCHEMBL12632559 | 0.83 | GRIA1 (0.57) | GRIA1CTSSCTSKCTSL | |
| SCHEMBL25139820 | 0.83 | GRIA1 (0.57) | GRIA1CTSSCTSKCTSL | |
| SCHEMBL30493746 | 0.83 | GRIA1 (0.61) | GRIA1OPRD1OPRM1OPRK1CTSS | |
| SCHEMBL29434521 | 0.82 | OPRD1 (0.60) | GRIA1OPRD1OPRM1OPRK1CTSS | |
| SCHEMBL18513842 | 0.81 | CTSS (0.54) | OPRD1OPRM1OPRK1CTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120264912-A1 | SELF-ASSEMBLING PEPTIDE AMPHIPHILES AND RELATED METHODS FOR GROWTH FACTOR DELIVERY | NORTHWESTERN UNIVERSITY (US) | 2012-10-18 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120264912-A1 | SELF-ASSEMBLING PEPTIDE AMPHIPHILES AND RELATED METHODS FOR GROWTH FACTOR DELIVERY | HDGF, HDGFL3, IAPP | GRIA1 1795/4885OPRD1 4235/4885OPRM1 3742/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.