Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GUSB | P08236 | 1/20 | 0.44 |
| ▸ | P2RY12 | Q9H244 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 10/20 | 0.42 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 3/20 | 0.41 |
| ▸ | PI4KA | P42356 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16334563 | 0.88 | PIK3CA (0.46) | PIK3CAMAPTLMNATP53PIK3CD | |
| SCHEMBL16335037 | 0.87 | HTT (0.46) | GUSBP2RY12MAPTLMNA | |
| SCHEMBL16335417 | 0.86 | ALPL (0.44) | PIK3CALMNAPIK3CGPI4KA | |
| SCHEMBL16335284 | 0.86 | MEN1 (0.54) | GUSBP2RY12MAPTLMNANPSR1 | |
| SCHEMBL16335125 | 0.85 | ALPL (0.54) | MAPTLMNATP53 | |
| SCHEMBL16335068 | 0.85 | CYP3A4 (0.47) | GUSBP2RY12MAPTLMNANPSR1 | |
| SCHEMBL1036460 | 0.84 | PIK3CA (0.46) | GUSBPIK3CAPIK3CGPIK3CDPIK3CB | |
| SCHEMBL16334725 | 0.83 | BCL2A1 (0.47) | GUSBP2RY12MAPTLMNA | |
| SCHEMBL16335056 | 0.81 | HTR7 (0.47) | GUSBMAPTLMNANPSR1 | |
| SCHEMBL16334201 | 0.81 | ALDH1A1 (0.58) | GUSBMAPTLMNATP53NPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2014207508-A1 | PYRIDYL COMPOUND SUITABLE FOR THE TREATMENT OF METABOLIC DISORDERS | Piramal Enterprises Limited (IN) | 2014-12-31 | — | — | WO | disclosed |