Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | REN | P00797 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.38 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.37 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | METAP2 | P50579 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | METAP1 | P53582 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | SLC18A2 | Q05940 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15648591 | 0.89 | RAB9A (0.40) | RAB9ATSHROPRM1SMN1; SMN2ALDH1A1 | |
| SCHEMBL13723227 | 0.86 | SLC6A2 (0.44) | RAB9AKCNH2TSHROPRM1ALDH1A1 | |
| SCHEMBL13731461 | 0.86 | SLC6A2 (0.43) | RAB9AC5AR1MAPTTSHROPRM1 | |
| SCHEMBL29368410 | 0.86 | SLC6A2 (0.43) | RAB9AC5AR1MAPTTSHROPRM1 | |
| SCHEMBL438859 | 0.86 | OPRM1 (0.40) | RAB9AMAPTTSHROPRM1ALDH1A1 | |
| SCHEMBL13724272 | 0.85 | SLC6A2 (0.38) | RAB9ATSHROPRM1ALDH1A1GPBAR1 | |
| SCHEMBL17431025 | 0.85 | AGER (0.46) | RAB9AOPRM1SIGMAR1GPBAR1 | |
| SCHEMBL15287094 | 0.85 | SLC6A2 (0.40) | RAB9AC5AR1TSHROPRM1SMN1; SMN2 | |
| SCHEMBL15525130 | 0.85 | RAB9A (0.36) | RAB9ARENCYP3A4KCNH2TSHR | |
| SCHEMBL16335462 | 0.83 | RAB9A (0.36) | RAB9AC5AR1TSHROPRM1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105339353-B | N- naphthenic base-N- [(fused phenyl) methylene]-(thio) carboxamides derivatives | 拜耳作物科学股份公司 | 2018-08-10 | — | — | CN | disclosed |
| EP-3013803-B1 | N-CYCLOALKYL-N-[(FUSEDPHENYL)METHYLENE]-(THIO)CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2018-05-16 | — | — | EP | disclosed |
| US-9765049-B2 | N-cycloalkyl-N-[(fusedphenyl)methylene]-(thio)carboxamide derivatives | BAYER CROPSCIENCE AG (DE) | 2017-09-19 | — | — | US | disclosed |
| US-20160185747-A1 | N-CYCLOALKYL-N-[(FUSEDPHENYL)METHYLENE]-(THIO)CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2016-06-30 | — | — | US | disclosed |
| EP-3013803-A1 | N-CYCLOALKYL-N-[(FUSEDPHENYL)METHYLENE]-(THIO)CARBOXAMIDE DERIVATIVES | Bayer CropScience AG (DE) | 2016-05-04 | — | — | EP | disclosed |
| WO-2014206954-A1 | N-CYCLOALKYL-N-[(FUSEDPHENYL)METHYLENE]-(THIO)CARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2014-12-31 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160185747-A1 | N-CYCLOALKYL-N-[(FUSEDPHENYL)METHYLENE]-(THIO)CARBOXAMIDE DERIVATIVES | CBR3, NANP, TPMT | RAB9A 2920/4885REN 1635/4885CYP3A4 62/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.