Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 6/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15648591 | 0.89 | RAB9A (0.40) | OPRM1RAB9ATSHRALDH1A1GPBAR1 | |
| SCHEMBL441106 | 0.88 | ALDH1A1 (0.35) | OPRM1ALDH1A1MEN1KMT2A | |
| SCHEMBL15525062 | 0.87 | CHRM2 (0.40) | OPRM1RAB9ATSHRALDH1A1GPBAR1 | |
| SCHEMBL12710329 | 0.87 | GPBAR1 (0.40) | OPRM1RAB9ATSHRALDH1A1GPBAR1 | |
| SCHEMBL13723227 | 0.86 | SLC6A2 (0.44) | OPRM1RAB9ATSHRALDH1A1GPBAR1 | |
| SCHEMBL13731461 | 0.86 | SLC6A2 (0.43) | OPRM1RAB9ATSHRALDH1A1GPBAR1 | |
| SCHEMBL16336161 | 0.86 | RAB9A (0.40) | OPRM1RAB9ATSHRALDH1A1GPBAR1 | |
| SCHEMBL29368410 | 0.86 | SLC6A2 (0.43) | OPRM1RAB9ATSHRALDH1A1GPBAR1 | |
| SCHEMBL13724272 | 0.85 | SLC6A2 (0.38) | OPRM1RAB9ATSHRALDH1A1GPBAR1 | |
| SCHEMBL17431025 | 0.85 | AGER (0.46) | OPRM1RAB9AGPBAR1TMEM97SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2908641-B1 | METHOD FOR TREATING PLANTS AGAINST FUNGI RESISTANT TO FUNGICIDES USING CARBOXAMIDE OR THIOCARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2018-01-10 | — | — | EP | claimed |
| US-9668480-B2 | Method for treating plants against fungi resistant to fungicides using carboxamide or thiocarboxamide derivatives | BAYER CROPSCIENCE AG (DE) | 2017-06-06 | — | — | US | claimed |
| US-20150264927-A1 | METHOD FOR TREATING PLANTS AGAINST FUNGI RESISTANT TO FUNGICIDES USING CARBOXAMIDE OR THIOCARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2015-09-24 | — | — | US | claimed |
| EP-2908641-A1 | METHOD FOR TREATING PLANTS AGAINST FUNGI RESISTANT TO FUNGICIDES USING CARBOXAMIDE OR THIOCARBOXAMIDE DERIVATIVES | Bayer Cropscience AG (DE) | 2015-08-26 | — | — | EP | claimed |
| WO-2014060520-A1 | METHOD FOR TREATING PLANTS AGAINST FUNGI RESISTANT TO FUNGICIDES USING CARBOXAMIDE OR THIOCARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2014-04-24 | — | — | WO | claimed |
| EP-3000809-B1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATIVES | BAYER IP GMBH (DE) | 2018-10-31 | — | — | EP | disclosed |
| EP-2908641-B1 | METHOD FOR TREATING PLANTS AGAINST FUNGI RESISTANT TO FUNGICIDES USING CARBOXAMIDE OR THIOCARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2018-01-10 | — | — | EP | disclosed |
| CN-107540615-A | fungicide pyrazole carboxamides derivatives | 拜尔农科股份公司 | 2018-01-05 | — | — | CN | disclosed |
| CN-102421757-B | Fungicide pyrazole carboxamide derivatives | 拜尔农科股份公司 | 2017-10-24 | — | — | CN | disclosed |
| US-9695126-B2 | Fungicide pyrazole carboxamides derivatives | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-07-04 | — | — | US | disclosed |
| US-9668480-B2 | Method for treating plants against fungi resistant to fungicides using carboxamide or thiocarboxamide derivatives | BAYER CROPSCIENCE AG (DE) | 2017-06-06 | — | — | US | disclosed |
| US-20160297766-A1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATIVES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2016-10-13 | — | — | US | disclosed |
| US-8772266-B2 | Fungicide pyrazole carboxamides derivates | BAYER CROPSCIENCE AG (DE) | 2014-07-08 | — | — | US | disclosed |
| US-20140148411-A1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATIVES | BAYER CROPSCIENCE AG | 2014-05-29 | — | — | US | disclosed |
| WO-2014060520-A1 | METHOD FOR TREATING PLANTS AGAINST FUNGI RESISTANT TO FUNGICIDES USING CARBOXAMIDE OR THIOCARBOXAMIDE DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2014-04-24 | — | — | WO | disclosed |
| CN-102421757-A | Fungicide pyrazole carboxamide derivatives | BAYER CROPSCIENCE AG | 2012-04-18 | — | — | CN | disclosed |
| EP-2430000-A2 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATIVES | Bayer CropScience Aktiengesellschaft (DE) | 2012-03-21 | — | — | EP | disclosed |
| US-20120065164-A1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATES | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2012-03-15 | — | — | US | disclosed |
| WO-2010130767-A2 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-11-18 | — | — | WO | disclosed |
| EP-2251331-A1 | Fungicide pyrazole carboxamides derivatives | Bayer CropScience AG (DE) | 2010-11-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140148411-A1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATIVES | CASP5, CBR3, CYP3A5 | OPRM1 3389/4885RAB9A 3110/4885TSHR 1515/4885 |
| US-20160297766-A1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATIVES | CASP5, CBR3, CYP3A5 | OPRM1 3389/4885RAB9A 3110/4885TSHR 1515/4885 |
| US-20150264927-A1 | METHOD FOR TREATING PLANTS AGAINST FUNGI RESISTANT TO FUNGICIDES USING CARBOXAMIDE OR THIOCARBOXAMIDE DERIVATIVES | SDHA, TPI1, CBR3 | OPRM1 4857/4885RAB9A 3062/4885TSHR 3047/4885 |
| US-20120065164-A1 | FUNGICIDE PYRAZOLE CARBOXAMIDES DERIVATES | CASP5, CTRL, CBR3 | OPRM1 3718/4885RAB9A 3223/4885TSHR 1514/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.