SCHEMBL16337442

SCHEMBL16337442

CCCCCCc1cc(C)c(N)c(C)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 4/20 0.53
SKP2 Q13309 1/20 0.53
CYP3A4 P08684 2/20 0.50
HTR2A P28223 1/20 0.48
GPR84 Q9NQS5 2/20 0.44
ESR1 P03372 2/20 0.44
ADRA2A P08913 2/20 0.44
ADORA3 P0DMS8 2/20 0.44
TACR2 P21452 2/20 0.44
SLC6A2 P23975 2/20 0.44
SLC6A4 P31645 2/20 0.44
SLC6A3 Q01959 2/20 0.44
KDM4E B2RXH2 2/20 0.44
ALDH1A1 P00352 2/20 0.44
HSD17B10 Q99714 2/20 0.44
HPGD P15428 2/20 0.44
RAB9A P51151 2/20 0.44
LMNA P02545 1/20 0.44
SHBG P04278 1/20 0.44
TP53 P04637 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18830614 1.00 PTGS2 (0.53) PTGS2SKP2CYP3A4HTR2AGPR84
SCHEMBL19480452 1.00 PTGS2 (0.53) PTGS2SKP2CYP3A4HTR2AGPR84
SCHEMBL11701754 0.91 SKP2 (0.62) PTGS2SKP2CYP3A4HTR2AGPR84
SCHEMBL27614083 0.83 PTGS2 (0.57) PTGS2SKP2CYP3A4HTR2AGPR84
SCHEMBL1183199 0.82 ALDH1A1 (0.48) SKP2CYP3A4KDM4EALDH1A1HPGD
SCHEMBL9122379 0.79 PTGS2 (0.70) PTGS2CYP3A4HTR2AGPR84ESR1
SCHEMBL8560359 0.79 PTGS2 (0.70) PTGS2CYP3A4HTR2AGPR84ESR1
SCHEMBL2153739 0.79 ALDH1A1 (0.55) PTGS2SKP2CYP3A4KDM4EALDH1A1
SCHEMBL7628223 0.79 PTGS2 (0.70) PTGS2CYP3A4HTR2AGPR84ESR1
SCHEMBL5610335 0.79 CYP3A4 (0.41) PTGS2SKP2CYP3A4KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11040992-B2 Light-emitting compound CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2021-06-22 US disclosed
EP-3438114-B1 METAL COMPLEX, COMPOSITION AND LIGHT-EMITTING DEVICE SUMITOMO CHEMICAL CO (JP) 2020-11-04 EP disclosed
US-20200270290-A1 LIGHT-EMITTING COMPOUND CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2020-08-27 US disclosed
EP-3295495-B1 LIGHT-EMITTING COMPOUND CAMBRIDGE DISPLAY TECH LTD (GB) 2020-08-26 EP disclosed
EP-3295495-B1 LIGHT-EMITTING COMPOUND CAMBRIDGE DISPLAY TECH LTD (GB) 2020-08-26 EP disclosed
US-20190185500-A1 METAL COMPLEX, COMPOSITION AND LIGHT EMITTING DEVICE SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2019-06-20 US disclosed
EP-3438114-A1 METAL COMPLEX, COMPOSITION AND LIGHT-EMITTING ELEMENT Sumitomo Chemical Company, Limited (JP) 2019-02-06 EP disclosed
EP-3438114-A1 METAL COMPLEX, COMPOSITION AND LIGHT-EMITTING ELEMENT Sumitomo Chemical Company, Limited (JP) 2019-02-06 EP disclosed
US-20180138426-A1 LIGHT-EMITTING COMPOUND CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2018-05-17 US disclosed
US-20180138426-A1 LIGHT-EMITTING COMPOUND CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2018-05-17 US disclosed
EP-3295495-A1 LIGHT-EMITTING COMPOUND Cambridge Display Technology Limited (GB) 2018-03-21 EP disclosed
WO-2017103599-A1 LIGHT-EMITTING COMPOUND CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2017-06-22 WO disclosed
WO-2017103599-A1 LIGHT-EMITTING COMPOUND CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2017-06-22 WO disclosed
WO-2016185183-A1 LIGHT-EMITTING COMPOUND CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2016-11-24 WO disclosed
WO-2016185183-A1 LIGHT-EMITTING COMPOUND CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) 2016-11-24 WO disclosed
US-20150001509-A1 COMPOSITION CAMBRIDGE DISPLAY TECHNOLOGY, LTD (GB) 2015-01-01 US disclosed
US-20150001509-A1 COMPOSITION CAMBRIDGE DISPLAY TECHNOLOGY, LTD (GB) 2015-01-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190185500-A1 METAL COMPLEX, COMPOSITION AND LIGHT EMITTING DEVICE CRY1, AP2M1, CHRM1 PTGS2 3027/4885SKP2 2776/4885CYP3A4 2108/4885
US-11040992-B2 Light-emitting compound ARL1, NR2E3, AR PTGS2 4190/4885SKP2 254/4885CYP3A4 2415/4885
US-20200270290-A1 LIGHT-EMITTING COMPOUND ARL1, NR2E3, AR PTGS2 4190/4885SKP2 254/4885CYP3A4 2415/4885
US-20180138426-A1 LIGHT-EMITTING COMPOUND CRY1, ARL1, C5 PTGS2 4344/4885SKP2 629/4885CYP3A4 1629/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.