Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNB2 | P17787 | 2/20 | 0.34 |
| ▸ | CHRNA4 | P43681 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | NR1D1 | P20393 | 1/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | CASP6 | P55212 | 1/20 | 0.32 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | PKM | P14618 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1634156 | 1.00 | CHRNB2 (0.34) | CHRNB2CHRNA4SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL1634155 | 1.00 | CHRNB2 (0.34) | CHRNB2CHRNA4SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL1632771 | 0.83 | ALDH1A1 (0.42) | SMN1; SMN2ALDH1A1MAPTPOLBPKM | |
| SCHEMBL1633061 | 0.80 | ALDH1A1 (0.33) | CHRNB2CHRNA4SMN1; SMN2ALDH1A1NR1D1 | |
| SCHEMBL12723280 | 0.79 | ALDH1A1 (0.35) | ALDH1A1MAPT | |
| SCHEMBL5593871 | 0.76 | ALDH1A1 (0.33) | SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7662760 | 0.75 | SMN1; SMN2 (0.37) | CHRNB2CHRNA4SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL1634269 | 0.74 | ALDH1A1 (0.39) | ALDH1A1MAPTPOLB | |
| SCHEMBL9319280 | 0.73 | ALDH1A1 (0.41) | SMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL7660230 | 0.73 | AGTR2 (0.39) | CHRNB2CHRNA4SMN1; SMN2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7932393-B2 | Insecticidal (heteroarylalky)alkane thio and oxo amine derivatives | FMC CORPORATION (US) | 2011-04-26 | — | — | US | disclosed |
| US-20100261757-A1 | Insecticidal (Heteroarylalky)alkane Thio and Oxo Amine Derivatives | FMC CORPORATION | 2010-10-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100261757-A1 | Insecticidal (Heteroarylalky)alkane Thio and Oxo Amine Derivatives | DDT, AKR7A2, TAAR1 | CHRNB2 1153/4885CHRNA4 1933/4885SMN1; SMN2 4132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.