Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1634351 | 1.00 | ALDH1A1 (0.38) | ALDH1A1TDP1TRPA1 | |
| SCHEMBL18556897 | 0.80 | GABRR1 (0.30) | — | |
| SCHEMBL9501448 | 0.74 | — | — | |
| SCHEMBL10399842 | 0.72 | — | — | |
| SCHEMBL10399841 | 0.72 | — | — | |
| SCHEMBL8601724 | 0.72 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL8601726 | 0.72 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL8601728 | 0.72 | ALDH1A1 (0.42) | ALDH1A1 | |
| SCHEMBL1785723 | 0.71 | — | — | |
| SCHEMBL20162280 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1989170-B1 | PROCESS FOR THE PREPARATION OF BETA-GAMMA ENE CARBONYL DERIVATIVES | FIRMENICH & CIE (CH) | 2018-04-11 | — | — | EP | disclosed |
| US-8632792-B2 | Cooling sensation agent composition and sensory stimulation agent composition | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2014-01-21 | — | — | US | disclosed |
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2011-05-19 | — | — | US | disclosed |
| US-7932418-B2 | Process for the preparation of β-γ ene carbonyl derivatives | FIRMENICH SA (CH) | 2011-04-26 | — | — | US | disclosed |
| US-20100168462-A1 | PROCESS FOR THE PREPARATION OF BETA-GAMMA ENE CARBONYL DERIVATIVES | FIRMENICH SA (CH) | 2010-07-01 | — | — | US | disclosed |
| EP-1989170-A1 | PROCESS FOR THE PREPARATION OF BETA-GAMMA ENE CARBONYL DERIVATIVES | Firmenich S.A. (CH) | 2008-11-12 | — | — | EP | disclosed |
| WO-2007096791-A1 | PROCESS FOR THE PREPARATION OF BETA-GAMMA ENE CARBONYL DERIVATIVES | FIRMENICH SA (CH) | 2007-08-30 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100168462-A1 | PROCESS FOR THE PREPARATION OF BETA-GAMMA ENE CARBONYL DERIVATIVES | GNE, ECH1, ECI1 | ALDH1A1 92/4885TDP1 4534/4885TRPA1 4152/4885 |
| US-20110117147-A1 | COOLING SENSATION AGENT COMPOSITION AND SENSORY STIMULATION AGENT COMPOSITION | TRPA1, HRH1, HRH2 | ALDH1A1 520/4885TDP1 3995/4885TRPA1 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.