SCHEMBL16343963

SCHEMBL16343963

c1ccc(Oc2ccc(Nc3ccc(-c4ccccc4)cc3)cc2)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 3/20 0.52
TSHR P16473 2/20 0.52
PTGS2 P35354 2/20 0.50
HSD17B10 Q99714 2/20 0.50
ALDH1A1 P00352 2/20 0.50
ALOX15 P16050 1/20 0.50
ALOX12 P18054 1/20 0.50
PTGS1 P23219 1/20 0.50
SLC6A2 P23975 1/20 0.50
MAPK1 P28482 1/20 0.50
HTR2B P41595 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
PGR P06401 3/20 0.48
GSTP1 P09211 1/20 0.48
FGFR2 P21802 1/20 0.48
SCN5A Q14524 1/20 0.47
SCN9A Q15858 1/20 0.47
ERBB2 P04626 1/20 0.47
KDR P35968 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8640958 0.93 ALDH1A1 (0.59) LTA4HTSHRPTGS2HSD17B10ALDH1A1
SCHEMBL14435643 0.91 LTA4H (0.63) LTA4HTSHRPTGS2HSD17B10ALDH1A1
SCHEMBL17948198 0.91 LTA4H (0.63) LTA4HTSHRPTGS2HSD17B10ALDH1A1
SCHEMBL7514685 0.89 ALDH1A1 (0.65) LTA4HTSHRPTGS2HSD17B10ALDH1A1
SCHEMBL8626416 0.86 ALDH1A1 (0.68) LTA4HTSHRPTGS2HSD17B10ALDH1A1
SCHEMBL13308524 0.86 ALDH1A1 (0.68) LTA4HTSHRPTGS2HSD17B10ALDH1A1
Biphenyl SCHEMBL10838288 0.86 LTA4H (0.71) LTA4HTSHRALDH1A1GSTP1NR1H2
SCHEMBL21921128 0.86 LTA4H (0.71) LTA4HTSHRALDH1A1GSTP1NR1H2
SCHEMBL403667 0.86 LTA4H (0.71) LTA4HTSHRALDH1A1GSTP1NR1H2
SCHEMBL9190364 0.86 LTA4H (0.71) LTA4HTSHRALDH1A1GSTP1NR1H2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021034089-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2021-02-25 WO disclosed
US-9748493-B2 Aromatic amine-terphenyl compounds and use thereof in organic semiconducting components NOVALED GMBH (DE) 2017-08-29 US disclosed
CN-104302618-A Aromatic amine-terphenyl compounds and use thereof in organic semiconducting components NOVALED GMBH 2015-01-21 CN disclosed
US-20150011795-A1 Aromatic Amine-Terphenyl Compounds and Use Thereof in Organic Semiconducting Components NOVALED GMBH (DE) 2015-01-08 US disclosed