SCHEMBL8626416

SCHEMBL8626416

c1ccc(Nc2ccc(Oc3ccc(Nc4ccccc4)cc3)cc2)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.68
HSD17B10 Q99714 5/20 0.68
L3MBTL1 Q9Y468 4/20 0.68
TSHR P16473 4/20 0.68
TDP1 Q9NUW8 4/20 0.68
ALOX12 P18054 3/20 0.68
MAPK1 P28482 2/20 0.68
ALOX15 P16050 2/20 0.68
PTGS1 P23219 1/20 0.68
SLC6A2 P23975 1/20 0.68
PTGS2 P35354 1/20 0.68
HTR2B P41595 1/20 0.68
MAPT P10636 5/20 0.55
GAA P10253 2/20 0.55
HSP90AA1 P07900 1/20 0.55
LTA4H P09960 1/20 0.55
CYP3A4 P08684 4/20 0.54
HPGD P15428 3/20 0.54
HTT P42858 2/20 0.54
CYP1A2 P05177 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13308524 1.00 ALDH1A1 (0.68) ALDH1A1HSD17B10L3MBTL1TSHRTDP1
SCHEMBL7514685 0.97 ALDH1A1 (0.65) ALDH1A1HSD17B10L3MBTL1TSHRTDP1
SCHEMBL14435643 0.95 LTA4H (0.63) ALDH1A1HSD17B10L3MBTL1TSHRTDP1
SCHEMBL17948198 0.95 LTA4H (0.63) ALDH1A1HSD17B10L3MBTL1TSHRTDP1
SCHEMBL8640958 0.93 ALDH1A1 (0.59) ALDH1A1HSD17B10L3MBTL1TSHRTDP1
SCHEMBL18657532 0.89 ALDH1A1 (0.67) ALDH1A1HSD17B10L3MBTL1TSHRTDP1
SCHEMBL2623469 0.87 ALDH1A1 (0.58) ALDH1A1HSD17B10L3MBTL1TSHRTDP1
SCHEMBL16343963 0.86 LTA4H (0.52) ALDH1A1HSD17B10L3MBTL1TSHRTDP1
SCHEMBL11644831 0.85 ALDH1A1 (0.62) ALDH1A1HSD17B10L3MBTL1TSHRTDP1
SCHEMBL20879853 0.84 LTA4H (0.50) ALDH1A1HSD17B10L3MBTL1TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109942456-B Method for synthesizing p-benzoquinone monoimine from p-aminophenol 宜宾学院 2021-05-04 CN disclosed
US-20140299864-A1 POLYMERS CONTAINING THERMALLY DISSOCIABLE AND SOLUBLE GROUPS AND THE USE OF SUCH POLYMERS AS ORGANIC ELECTROLUMINESCENT MATERIALS MITSUBISHI CHEMICAL CORPORATION (JP) 2014-10-09 US disclosed
US-8795849-B2 Polymers containing thermally dissociable and soluble groups and the use of such polymers as organic electroluminescent materials MITSUBISHI CHEMICAL CORPORATION (JP) 2014-08-05 US disclosed
US-20120193617-A1 LOW-MOLECULAR COMPOUND, POLYMER, ELECTRONIC-DEVICE MATERIAL, COMPOSITION FOR ELECTRONIC DEVICE, ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC SOLAR CELL ELEMENT, DISPLAY AND LIGHTING MITSUBISHI CHEMICAL CORPORATION (JP) 2012-08-02 US disclosed
EP-0452681-B1 Electrostatographic imaging member containing polyarylamine polymers XEROX CORP (US) 1998-06-03 EP disclosed
EP-0452682-B1 Polyarylamine polymers XEROX CORP (US) 1997-09-17 EP disclosed
US-5356743-A Electrophotographic imaging members containing polyarylamine polyesters XEROX CORPORATION (US) 1994-10-18 US disclosed
EP-0295113-B1 Polyarylamine compounds XEROX CORP (US) 1994-02-02 EP disclosed
US-5283143-A Electrophotographic imaging member containing arylamine terpolymers with CF3 substituted moieties XEROX CORPORATION (US) 1994-02-01 US disclosed
US-5262512-A Polyarylamine polyesters XEROX CORPORATION (US) 1993-11-16 US disclosed
US-5202408-A Arylamine containing terpolymers with CF3 substituted moieties XEROX CORPORATION (US) 1993-04-13 US disclosed
US-5155200-A Polyurethanes from dihydroxyarylamine compounds XEROX CORPORATION (US) 1992-10-13 US disclosed
EP-0452682-A2 Polyarylamine polymers XEROX CORPORATION (US) 1991-10-23 EP disclosed
EP-0452681-A2 Systems utilizing polyarylamine polymers XEROX CORPORATION (US) 1991-10-23 EP disclosed
US-5030532-A Electrophotographic imaging member utilizing polyarylamine polymers XEROX CORPORATION (US) 1991-07-09 US disclosed
US-4801517-A Polyarylamine compounds and systems utilizing polyarylamine compounds XEROX CORPORATION (US) 1989-01-31 US disclosed
EP-0035530-B1 IMAGEABLE, COMPOSITE DRY-TRANSFER SHEET MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1985-10-23 EP disclosed
US-4291114-A COMPRISING A PHOTOPOLYMERIZABLE LAYER OF A MONOMER AND A CATIONIC PROMOTER ON AN OLEOPHILIC SURFACE OF A COVERING MINNESOTA MINING AND MANUFACTURING CO. (US) 1981-09-22 US disclosed
US-4069054-A Photopolymerizable composition containing a sensitized aromatic sulfonium compound and a cationacally polymerizable monomer MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1978-01-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120193617-A1 LOW-MOLECULAR COMPOUND, POLYMER, ELECTRONIC-DEVICE MATERIAL, COMPOSITION FOR ELECTRONIC DEVICE, ORGANIC ELECTROLUMINESCENT ELEMENT, ORGANIC SOLAR CELL ELEMENT, DISPLAY AND LIGHTING EPCAM, CDH1, THEM6 ALDH1A1 2277/4885HSD17B10 4144/4885L3MBTL1 1397/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.