Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16348290 | 0.86 | RNPEP (0.35) | ALDH1A1RNPEPFOLH1NPC1MAPT | |
| SCHEMBL17971010 | 0.83 | TSHR (0.43) | ALDH1A1TDP1CYP2C19CA2FOLH1 | |
| SCHEMBL16328450 | 0.82 | GABRP (0.37) | ALDH1A1RNPEPFOLH1 | |
| SCHEMBL16312929 | 0.77 | TSHR (0.43) | ALDH1A1TDP1CYP2C19CA2ACHE | |
| SCHEMBL14763545 | 0.75 | — | — | |
| SCHEMBL13879345 | 0.74 | ALDH1A1 (0.48) | ALDH1A1TDP1CYP2C19CA2RNPEP | |
| SCHEMBL16328449 | 0.73 | ANPEP (0.32) | RNPEPFOLH1 | |
| SCHEMBL36990 | 0.73 | CYP2C19 (0.59) | ALDH1A1TDP1CYP2C19CA2ACHE | |
| SCHEMBL10834211 | 0.73 | CYP2C19 (0.59) | ALDH1A1TDP1CYP2C19CA2ACHE | |
| SCHEMBL2532013 | 0.72 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7879588-B2 | Protein-proteophore complexes | ASCENDIS PHARMA A/S (DK) | 2011-02-01 | — | — | US | disclosed |