Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.35 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16348289 | 0.86 | ALDH1A1 (0.40) | RNPEPFOLH1ALDH1A1NPC1MAPT | |
| SCHEMBL16328450 | 0.82 | GABRP (0.37) | RNPEPFOLH1ALDH1A1 | |
| SCHEMBL16328449 | 0.73 | ANPEP (0.32) | RNPEPFOLH1 | |
| SCHEMBL812086 | 0.72 | — | — | |
| SCHEMBL12943418 | 0.72 | — | — | |
| SCHEMBL2050674 | 0.72 | CES2 (0.43) | ALDH1A1 | |
| SCHEMBL13423113 | 0.70 | — | — | |
| SCHEMBL11535513 | 0.70 | — | — | |
| SCHEMBL19674985 | 0.70 | ALDH1A1 (0.50) | ALDH1A1 | |
| SCHEMBL1329635 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7879588-B2 | Protein-proteophore complexes | ASCENDIS PHARMA A/S (DK) | 2011-02-01 | — | — | US | disclosed |