Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1G | O43497 | 3/20 | 0.45 |
| ▸ | CACNA1I | Q9P0X4 | 3/20 | 0.45 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.45 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.44 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.44 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13523181 | 0.81 | IDO1 (0.44) | HPGDMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL16348322 | 0.78 | IDO1 (0.41) | HPGDMEN1KMT2AALOX15CYP3A4 | |
| SCHEMBL16348315 | 0.77 | MAPT (0.45) | HPGDMEN1KMT2AALOX15LMNA | |
| SCHEMBL16348338 | 0.77 | IDO1 (0.42) | HPGDMEN1KMT2ALMNAALDH1A1 | |
| SCHEMBL31128113 | 0.76 | LMNA (0.57) | CACNA1GCACNA1ICACNA1HHPGDMEN1 | |
| SCHEMBL16348314 | 0.75 | PPARA (0.52) | CACNA1GCACNA1ICACNA1HCACNA1CHPGD | |
| SCHEMBL16348318 | 0.74 | PTGER1 (0.39) | CACNA1GCACNA1ICACNA1HCACNA1CHPGD | |
| SCHEMBL366947 | 0.74 | IDO1 (0.50) | HPGDMEN1KMT2AALOX15HSD17B10 | |
| SCHEMBL9820215 | 0.74 | ALDH1A1 (0.47) | CACNA1GCACNA1IHPGDMEN1KMT2A | |
| SCHEMBL23923762 | 0.73 | NPC1 (0.46) | CACNA1GCACNA1ICACNA1HCACNA1CHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |