Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER1 | P34995 | 8/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 3/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.37 |
| ▸ | RELA | Q04206 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.37 |
| ▸ | CACNA1G | O43497 | 3/20 | 0.36 |
| ▸ | CACNA1H | O95180 | 3/20 | 0.36 |
| ▸ | CACNA1I | Q9P0X4 | 3/20 | 0.36 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16348314 | 0.75 | PPARA (0.52) | PTGER1ALDH1A1NPC1LMNARAB9A | |
| SCHEMBL16348304 | 0.74 | CACNA1G (0.45) | PTGER1ALDH1A1NPC1LMNARAB9A | |
| SCHEMBL16348340 | 0.74 | PTGER1 (0.41) | PTGER1ALDH1A1NPC1LMNARAB9A | |
| SCHEMBL16348397 | 0.70 | KDM4E (0.36) | ALDH1A1NPC1RAB9AKDM4EHPGD | |
| SCHEMBL16348319 | 0.68 | ACSS2 (0.40) | PTGER1NPC1RAB9ACYP2C9SMN1; SMN2 | |
| SCHEMBL31128113 | 0.68 | LMNA (0.57) | ALDH1A1NPC1LMNARAB9AKDM4E | |
| SCHEMBL16348381 | 0.66 | RAB9A (0.39) | PTGER1NPC1RAB9AKDM4EHTT | |
| SCHEMBL2989844 | 0.66 | S1PR4 (0.42) | NPC1LMNARAB9AHPGDSMN1; SMN2 | |
| SCHEMBL12378188 | 0.65 | CYP1A2 (0.43) | ALDH1A1NPC1LMNARAB9AKDM4E | |
| SCHEMBL7494123 | 0.64 | RAB9A (0.68) | ALDH1A1NPC1LMNARAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |