Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.47 |
| ▸ | PPARA | Q07869 | 4/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | TSPO | P30536 | 1/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.35 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.35 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.35 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.35 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.35 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16348369 | 0.95 | PPARA (0.48) | PPARGPPARACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL16348426 | 0.90 | PSEN1 (0.38) | PPARGPPARACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL16348306 | 0.90 | PPARG (0.51) | PPARGPPARACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL16348339 | 0.87 | PPARG (0.39) | PPARGPPARACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL16348313 | 0.86 | PPARG (0.44) | PPARGPPARA | |
| SCHEMBL16348334 | 0.85 | PPARG (0.55) | PPARGPPARATSPOKEAP1NFE2L2 | |
| SCHEMBL16348309 | 0.85 | PPARA (0.52) | PPARGPPARACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL16348423 | 0.83 | PPARG (0.46) | PPARGPPARACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL16350102 | 0.83 | PPARG (0.46) | PPARGPPARACYP1A2CYP2D6CYP2C19 | |
| SCHEMBL16348327 | 0.82 | PPARA (0.46) | PPARGPPARACYP1A2CYP2D6CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |