Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.39 |
| ▸ | PPARA | Q07869 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | TSPO | P30536 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.36 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.35 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16348369 | 0.92 | PPARA (0.48) | PPARGPPARAALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL16348362 | 0.91 | PPARG (0.42) | PPARGPPARAALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL16348340 | 0.88 | PTGER1 (0.41) | PPARGPPARAALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL16348426 | 0.87 | PSEN1 (0.38) | PPARGPPARAALDH1A1MEN1CYP1A2 | |
| SCHEMBL16348357 | 0.87 | PPARG (0.47) | PPARGPPARAALDH1A1MEN1CYP1A2 | |
| SCHEMBL16348364 | 0.86 | PPARG (0.45) | PPARGPPARAALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL16348310 | 0.85 | PPARG (0.41) | PPARGPPARAALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL16348309 | 0.82 | PPARA (0.52) | PPARGPPARAALDH1A1NPSR1L3MBTL1 | |
| SCHEMBL16348368 | 0.81 | PPARG (0.38) | PPARGLMNAMAPT | |
| SCHEMBL16348313 | 0.81 | PPARG (0.44) | PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |
| US-7642358-B2 | Substituted phenylacetic acids | METABOLEX, INC. (US) | 2010-01-05 | — | — | US | disclosed |